Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2514848..2515032 Replicon chromosome
Accession NC_017763
Organism Staphylococcus aureus subsp. aureus HO 5096 0412

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SAEMRSA15_RS12830 Protein ID WP_000482647.1
Coordinates 2514925..2515032 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2514848..2514908 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAEMRSA15_RS12815 2510644..2512377 - 1734 WP_000486501.1 ABC transporter ATP-binding protein/permease -
SAEMRSA15_RS12820 2512402..2514165 - 1764 WP_001064811.1 ABC transporter ATP-binding protein/permease -
- 2514848..2514908 + 61 - - Antitoxin
SAEMRSA15_RS12830 2514925..2515032 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SAEMRSA15_RS12835 2515166..2515552 - 387 WP_000779356.1 flippase GtxA -
SAEMRSA15_RS12840 2515820..2516962 + 1143 WP_001176863.1 glycerate kinase -
SAEMRSA15_RS12845 2517022..2517681 + 660 WP_000831298.1 membrane protein -
SAEMRSA15_RS12850 2517860..2519071 + 1212 WP_001191976.1 multidrug effflux MFS transporter -
SAEMRSA15_RS12855 2519194..2519667 - 474 WP_000456498.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T27705 WP_000482647.1 NC_017763:c2515032-2514925 [Staphylococcus aureus subsp. aureus HO 5096 0412]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T27705 NC_017763:c2515032-2514925 [Staphylococcus aureus subsp. aureus HO 5096 0412]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT27705 NC_017763:2514848-2514908 [Staphylococcus aureus subsp. aureus HO 5096 0412]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References