Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 733641..734334 Replicon chromosome
Accession NZ_CP122499
Organism Escherichia coli strain W409

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag QC809_RS03635 Protein ID WP_063084548.1
Coordinates 733641..733937 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID S1EBV2
Locus tag QC809_RS03640 Protein ID WP_000650107.1
Coordinates 733939..734334 (+) Length 132 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC809_RS03600 (728729) 728729..729043 - 315 WP_063084545.1 putative quinol monooxygenase -
QC809_RS03605 (729074) 729074..729655 - 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
QC809_RS03610 (729974) 729974..730306 + 333 WP_000917684.1 DUF2645 family protein -
QC809_RS03615 (730352) 730352..731701 - 1350 WP_063084546.1 quorum sensing histidine kinase QseC -
QC809_RS03620 (731698) 731698..732357 - 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB -
QC809_RS03625 (732509) 732509..732901 + 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
QC809_RS03630 (732954) 732954..733436 + 483 WP_000183505.1 GyrI-like domain-containing protein -
QC809_RS03635 (733641) 733641..733937 + 297 WP_063084548.1 type II toxin-antitoxin system toxin MqsR Toxin
QC809_RS03640 (733939) 733939..734334 + 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA Antitoxin
QC809_RS03645 (734467) 734467..736074 + 1608 WP_001295629.1 ABC transporter substrate-binding protein -
QC809_RS03650 (736212) 736212..738470 + 2259 WP_001281841.1 DNA topoisomerase IV subunit A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Zinc finger, MqsA-type

(3-47)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11290.00 Da        Isoelectric Point: 8.0440

>T277046 WP_063084548.1 NZ_CP122499:733641-733937 [Escherichia coli]
MEKRTPHTRLSQVKKLVNAGQVRTTRSALLNADELDLDFDGMCNVIIGLSESDFYKSMTTYSDHTIWQDVYRPRLVTGQV
YLKITVIHDVLIVSFKEK

Download         Length: 297 bp

Antitoxin


Download         Length: 132 a.a.        Molecular weight: 14703.10 Da        Isoelectric Point: 9.2136

>AT277046 WP_000650107.1 NZ_CP122499:733939-734334 [Escherichia coli]
MKCPVCHQGEMVSGIKDIPYTFRGRKTVLKGIHGLYCVHCEESIMNKEESDAFMAQVKAFRASVNAETVAPEFIVKVRKK
LSLTQKEASEIFGGGVNAFSRYEKGNAQPHPSTIKLLRVLDKHPELLNEIR

Download         Length: 396 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
PDB 3HI2
PDB 3GA8
PDB 3O9X
PDB 2KZ8
PDB 3FMY
PDB 3GN5
AlphaFold DB A0A7U9LU65

References