Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2228016..2228233 Replicon chromosome
Accession NC_017763
Organism Staphylococcus aureus subsp. aureus HO 5096 0412

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag SAEMRSA15_RS11315 Protein ID WP_075583739.1
Coordinates 2228129..2228233 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2228016..2228071 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAEMRSA15_RS11295 2224072..2224737 - 666 WP_001024097.1 SDR family oxidoreductase -
SAEMRSA15_RS11300 2224889..2225209 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAEMRSA15_RS11305 2225211..2226191 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
SAEMRSA15_RS11310 2226457..2227548 + 1092 WP_000495678.1 hypothetical protein -
- 2228016..2228071 + 56 - - Antitoxin
SAEMRSA15_RS11315 2228129..2228233 - 105 WP_075583739.1 hypothetical protein Toxin
SAEMRSA15_RS14925 2228331..2228492 - 162 Protein_2139 helix-turn-helix domain-containing protein -
SAEMRSA15_RS15260 2228910..2229068 + 159 WP_024928151.1 hypothetical protein -
SAEMRSA15_RS11325 2229728..2230585 - 858 WP_000370944.1 Cof-type HAD-IIB family hydrolase -
SAEMRSA15_RS11330 2230653..2231435 - 783 WP_000908181.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-128)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T27702 WP_075583739.1 NC_017763:c2228233-2228129 [Staphylococcus aureus subsp. aureus HO 5096 0412]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

>T27702 NC_017763:c2228233-2228129 [Staphylococcus aureus subsp. aureus HO 5096 0412]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTAATCAAGGCCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT27702 NC_017763:2228016-2228071 [Staphylococcus aureus subsp. aureus HO 5096 0412]
AAAAAGGGCAACACTCAGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References