Detailed information of TA system TA027695

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1895456..1895636
• Replicon: chromosome
• Accession: NC_017763
• Organism: Staphylococcus aureus subsp. aureus HO 5096 0412

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAEMRSA15_RS15220
• Protein ID: WP_001801861.1
• Coordinates: 1895456..1895551 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1895579..1895636 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAEMRSA15_RS09265	1890743..1891510	-	768	WP_001095317.1	IS21-like element helper ATPase IstB	-
SAEMRSA15_RS09270	1891522..1892757	-	1236	WP_001215400.1	IS21 family transposase	-
SAEMRSA15_RS09275	1893115..1893684	-	570	WP_000864144.1	ImmA/IrrE family metallo-endopeptidase	-
SAEMRSA15_RS09280	1893870..1894055	-	186	WP_000809864.1	hypothetical protein	-
SAEMRSA15_RS09285	1894057..1894233	-	177	WP_000375476.1	hypothetical protein	-
SAEMRSA15_RS09290	1894244..1894627	-	384	WP_000070809.1	hypothetical protein	-
SAEMRSA15_RS09295	1894809..1895033	-	225	WP_001805677.1	IS3 family transposase	-
SAEMRSA15_RS14800	1895207..1895311	-	105	WP_001670380.1	transposase	-
SAEMRSA15_RS15220	1895456..1895551	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1895579..1895636	-	58	-	-	Antitoxin
SAEMRSA15_RS09300	1895674..1895775	+	102	WP_001791232.1	hypothetical protein	-
SAEMRSA15_RS15225	1895753..1895925	-	173	Protein_1788	transposase	-
SAEMRSA15_RS09305	1896119..1896496	-	378	WP_001036002.1	DUF1433 domain-containing protein	-
SAEMRSA15_RS09310	1896702..1897142	-	441	WP_000759947.1	DUF1433 domain-containing protein	-
SAEMRSA15_RS09315	1897187..1898800	+	1614	WP_000926708.1	lipase	-
SAEMRSA15_RS09320	1898815..1899114	+	300	WP_000095392.1	WXG100 family type VII secretion target	-
SAEMRSA15_RS09325	1899431..1900612	-	1182	WP_000162901.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	1866105..1911866	45761

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T27695 WP_001801861.1 NC_017763:1895456-1895551 [Staphylococcus aureus subsp. aureus HO 5096 0412]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T27695 NC_017763:1895456-1895551 [Staphylococcus aureus subsp. aureus HO 5096 0412]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT27695 NC_017763:c1895636-1895579 [Staphylococcus aureus subsp. aureus HO 5096 0412]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin