Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 594657..595456 Replicon chromosome
Accession NZ_CP122451
Organism Escherichia coli strain 82.0312

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag QBY78_RS02915 Protein ID WP_087598199.1
Coordinates 594657..595121 (-) Length 155 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag QBY78_RS02920 Protein ID WP_087598198.1
Coordinates 595121..595456 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QBY78_RS02885 (589658) 589658..590092 - 435 WP_000948837.1 PTS galactosamine/N-acetylgalactosamine transporter subunit IIA -
QBY78_RS02890 (590110) 590110..590988 - 879 WP_001295548.1 PTS N-acetylgalactosamine transporter subunit IID -
QBY78_RS02895 (590978) 590978..591757 - 780 WP_000406214.1 PTS N-acetylgalactosamine transporter subunit IIC -
QBY78_RS02900 (591768) 591768..592241 - 474 WP_001295547.1 PTS N-acetylgalactosamine transporter subunit IIB -
QBY78_RS02905 (592264) 592264..593544 - 1281 WP_052925113.1 tagatose-bisphosphate aldolase subunit KbaZ -
QBY78_RS02910 (593793) 593793..594602 + 810 WP_000072187.1 aga operon transcriptional regulator AgaR -
QBY78_RS02915 (594657) 594657..595121 - 465 WP_087598199.1 type II toxin-antitoxin system ribonuclease toxin YhaV Toxin
QBY78_RS02920 (595121) 595121..595456 - 336 WP_087598198.1 type II toxin-antitoxin system antitoxin PrlF Antitoxin
QBY78_RS02925 (595605) 595605..597176 - 1572 WP_001273940.1 galactarate dehydratase -
QBY78_RS02930 (597551) 597551..598885 + 1335 WP_000979025.1 galactarate/glucarate/glycerate transporter GarP -
QBY78_RS02935 (598901) 598901..599671 + 771 WP_001058227.1 2-dehydro-3-deoxyglucarate aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-150)

Antitoxin

PrlF antitoxin

(14-110)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 17811.16 Da        Isoelectric Point: 9.4947

>T276896 WP_087598199.1 NZ_CP122451:c595121-594657 [Escherichia coli]
MDFPQRVNGWALYAHPCFQETYDAFVAEVEALKGKDPENYQRKAATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKN
KDWSRVKFGAGRYRLFFRYSEKEKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWESLTQETEENH

Download         Length: 465 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12303.88 Da        Isoelectric Point: 4.5392

>AT276896 WP_087598198.1 NZ_CP122451:c595456-595121 [Escherichia coli]
MPANARSNAVLTTESKVTIRGQTTIPAPVREALKLKPGLDSIHYEILPGGQVFLCRLGDEQEDHTMNAFLRFLDADIQNN
PQKTRPFDIQQGKKLVAGMDVNIDDEIGDDE

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References