Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 2078183..2078793 Replicon chromosome
Accession NZ_CP122407
Organism Rugamonas sp. DEMB1

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag QC826_RS09665 Protein ID WP_279765396.1
Coordinates 2078515..2078793 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QC826_RS09660 Protein ID WP_279765395.1
Coordinates 2078183..2078491 (-) Length 103 a.a.

Genomic Context

QC826_RS09640QC826_RS09645QC826_RS09650QC826_RS09675QC826_RS09625QC826_RS09630QC826_RS09635QC826_RS09655QC826_RS09660QC826_RS09665QC826_RS09670QC826_RS09680QC826_RS09685
Location: 2076262..2076747 (486 bp)
Type: Others
Protein ID: WP_279765392.1
Location: 2076740..2077051 (312 bp)
Type: Others
Protein ID: WP_093386726.1
Location: 2077159..2077776 (618 bp)
Type: Others
Protein ID: WP_279765393.1
Location: 2080481..2080825 (345 bp)
Type: Others
Protein ID: WP_093386711.1
Location: 2074164..2075060 (897 bp)
Type: Others
Protein ID: WP_279765389.1
Location: 2075149..2075586 (438 bp)
Type: Others
Protein ID: WP_279765390.1
Location: 2075691..2076197 (507 bp)
Type: Others
Protein ID: WP_279765391.1
Location: 2077832..2078164 (333 bp)
Type: Others
Protein ID: WP_279765394.1
Location: 2078183..2078491 (309 bp)
Type: Antitoxin
Protein ID: WP_279765395.1
Location: 2078515..2078793 (279 bp)
Type: Toxin
Protein ID: WP_279765396.1
Location: 2078963..2080225 (1263 bp)
Type: Others
Protein ID: WP_279765397.1
Location: 2080931..2081846 (916 bp)
Type: Others
Protein ID: Protein_1890
Location: 2081843..2083033 (1191 bp)
Type: Others
Protein ID: WP_279765398.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QC826_RS09625 (QC826_09625)2074164..2075060-897WP_279765389.1alpha/beta hydrolase-
QC826_RS09630 (QC826_09630)2075149..2075586-438WP_279765390.1MarR family transcriptional regulator-
QC826_RS09635 (QC826_09635)2075691..2076197-507WP_279765391.1carboxymuconolactone decarboxylase family protein-
QC826_RS09640 (QC826_09640)2076262..2076747+486WP_279765392.1MarR family transcriptional regulator-
QC826_RS09645 (QC826_09645)2076740..2077051+312WP_093386726.1Dabb family protein-
QC826_RS09650 (QC826_09650)2077159..2077776+618WP_279765393.12-hydroxychromene-2-carboxylate isomerase-
QC826_RS09655 (QC826_09655)2077832..2078164-333WP_279765394.1hypothetical protein-
QC826_RS09660 (QC826_09660)2078183..2078491-309WP_279765395.1HigA family addiction module antitoxinAntitoxin
QC826_RS09665 (QC826_09665)2078515..2078793-279WP_279765396.1type II toxin-antitoxin system RelE/ParE family toxinToxin
QC826_RS09670 (QC826_09670)2078963..2080225-1263WP_279765397.1D-amino acid dehydrogenase-
QC826_RS09675 (QC826_09675)2080481..2080825+345WP_093386711.1zinc ribbon domain-containing protein YjdM-
QC826_RS09680 (QC826_09680)2080931..2081846-916Protein_18903-hydroxyisobutyrate dehydrogenase-
QC826_RS09685 (QC826_09685)2081843..2083033-1191WP_279765398.1enoyl-CoA hydratase/isomerase family protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(24-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(22-69)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10602.14 Da        Isoelectric Point: 9.2231

>T276842 WP_279765396.1 NZ_CP122407:c2078793-2078515 [Rugamonas sp. DEMB1]
MIISFACSETEALFNSLSVRHFKNIERSARRKLLQLNAAGELRSLRIPPGNMLEALSGSRKGQYSIRINDQWRICFKWQA
DGPHDVEIVDYH

Download         Length: 279 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11718.54 Da        Isoelectric Point: 5.6920

>AT276842 WP_279765395.1 NZ_CP122407:c2078491-2078183 [Rugamonas sp. DEMB1]
MAKLLDEVHPGEILLEEFMRPLGITAQQLAADIDVSPSRISDIVHGNRPITADTALRLGLFFDMEARYWLNLQSEYDMRI
AQRTLKDQLAPRIRVYQPVRPT

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References