276804

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 1560416..1561746 Replicon chromosome
Accession NZ_CP122328
Organism Pantoea agglomerans pv. betae strain 4188

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag A7P61_RS11445 Protein ID WP_064703683.1
Coordinates 1560416..1561438 (-) Length 341 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag A7P61_RS11450 Protein ID WP_031591302.1
Coordinates 1561435..1561746 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7P61_RS11430 (A7P61_11430) 1556564..1557586 + 1023 WP_010247994.1 LLM class flavin-dependent oxidoreductase -
A7P61_RS11435 (A7P61_11435) 1557702..1557884 + 183 Protein_1404 hypothetical protein -
A7P61_RS11440 (A7P61_11440) 1558072..1560291 + 2220 WP_064703684.1 catalase/peroxidase HPI -
A7P61_RS11445 (A7P61_11445) 1560416..1561438 - 1023 WP_064703683.1 HipA domain-containing protein Toxin
A7P61_RS11450 (A7P61_11450) 1561435..1561746 - 312 WP_031591302.1 HipA N-terminal domain-containing protein Antitoxin
A7P61_RS11455 (A7P61_11455) 1561731..1562066 - 336 WP_064703682.1 hypothetical protein -
A7P61_RS11465 (A7P61_11465) 1562843..1563964 + 1122 WP_064703681.1 Gfo/Idh/MocA family oxidoreductase -
A7P61_RS11470 (A7P61_11470) 1564055..1564885 - 831 WP_064703680.1 glycosyltransferase family 8 protein -
A7P61_RS11475 (A7P61_11475) 1564898..1566280 - 1383 WP_064703679.1 D-arabinono-1,4-lactone oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(58-302)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 341 a.a.        Molecular weight: 38535.06 Da        Isoelectric Point: 6.6643

>T276804 WP_064703683.1 NZ_CP122328:c1561438-1560416 [Pantoea agglomerans pv. betae]
MNSERCLITLKRLKESELKTGYSTKGIRHLLGSLNVALSLPFTRSQFIQELPERQKGMSISGYQPKLSLRLAKGELVVVS
NDGTYILKPSPEEYPHLAENEHATMCVMQRLKFDVPPFGLMPFRHDENRPDELAFVIQRYDRTASDNARLHQEQLDGAMG
PGDKYGRIDNHKAISYEKAAKFLNTRVNSSLKSKRDLFLRIVYAYVLGNNDFHLRNIGIILPPQGSPWLAPVYDFISLVP
YPAAFGEYLALPLLEREENDAGNAPGMNSEYGEYLGADFILLAQGMDINPTLARKWLSEVVSHHQLIIDTYNESHMPESQ
REAVLDYVARRITLLAVTEI

Download         Length: 1023 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11696.49 Da        Isoelectric Point: 4.7953

>AT276804 WP_031591302.1 NZ_CP122328:c1561746-1561435 [Pantoea agglomerans pv. betae]
MARKIEVWLYNTLAGTLSEGQNGYTFCYLPTYVGCAISLSMPVRPEPYLSEELHPFFKGLAPEGWLRKRYSEIQKIDDKD
LFGLLMENGNDLLGAVVFKEITS

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References