Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 113232..113764 Replicon plasmid pPATHpab
Accession NZ_CP122327
Organism Pantoea agglomerans pv. betae strain 4188

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag A7P61_RS03945 Protein ID WP_064703620.1
Coordinates 113489..113764 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag A7P61_RS03940 Protein ID WP_064703619.1
Coordinates 113232..113489 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7P61_RS03920 (A7P61_03920) 108383..109606 + 1224 WP_283833883.1 type III secretion system effector HopQ1-1 -
A7P61_RS03925 (A7P61_03925) 109722..111839 - 2118 WP_283833880.1 type III secretion system effector HopD1 -
A7P61_RS03930 (A7P61_03930) 112115..112216 + 102 Protein_113 IS6 family transposase -
A7P61_RS03935 (A7P61_03935) 112200..112925 + 726 WP_074399967.1 DUF1173 family protein -
A7P61_RS03940 (A7P61_03940) 113232..113489 + 258 WP_064703619.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
A7P61_RS03945 (A7P61_03945) 113489..113764 + 276 WP_064703620.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
A7P61_RS03950 (A7P61_03950) 113854..114086 - 233 Protein_117 transposase -
A7P61_RS03955 (A7P61_03955) 114090..114206 - 117 Protein_118 transposase -
A7P61_RS03960 (A7P61_03960) 114262..114776 - 515 Protein_119 helix-turn-helix domain-containing protein -
A7P61_RS03965 (A7P61_03965) 115110..115352 + 243 WP_064703622.1 hypothetical protein -
A7P61_RS03970 (A7P61_03970) 115381..116913 - 1533 WP_064703623.1 type III helper protein HopAK1 -
A7P61_RS03975 (A7P61_03975) 117389..117606 + 218 Protein_122 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - pla 1..156057 156057


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10745.34 Da        Isoelectric Point: 8.4536

>T276802 WP_064703620.1 NZ_CP122327:113489-113764 [Pantoea agglomerans pv. betae]
MLTPVQASAFKRDIKRQQKRGKDMTKLKTLIKLLVEEKEIPPEYEDHPLQGDWRGYRDAHMEGDWILIYKVEGTDLKLAR
TGTHQEIFSNY

Download         Length: 276 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9434.83 Da        Isoelectric Point: 5.8562

>AT276802 WP_064703619.1 NZ_CP122327:113232-113489 [Pantoea agglomerans pv. betae]
MNADAMVRARIPKDTKDRAVAALDKIGLSTSDVIRLVMMRVAEEGRLPFEVKTPNSATRRAMDELENGHGKRFETADALF
DDMGI

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References