276792

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 160512..161333 Replicon plasmid pPAG02
Accession NZ_CP122321
Organism Pantoea agglomerans pv. gypsophilae strain 824-1

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag A7P62_RS20120 Protein ID WP_064690735.1
Coordinates 160863..161333 (+) Length 157 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A8X8DUC8
Locus tag A7P62_RS20115 Protein ID WP_033773852.1
Coordinates 160512..160856 (+) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7P62_RS20095 (A7P62_20095) 156512..157621 + 1110 WP_064690732.1 maltose/maltodextrin ABC transporter ATP-binding protein MalK -
A7P62_RS20100 (A7P62_20100) 157665..158966 + 1302 WP_033760237.1 maltoporin -
A7P62_RS20105 (A7P62_20105) 159069..160007 + 939 WP_064690733.1 maltose operon protein MalM -
A7P62_RS20110 (A7P62_20110) 160197..160412 + 216 WP_064690734.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
A7P62_RS20115 (A7P62_20115) 160512..160856 + 345 WP_033773852.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
A7P62_RS20120 (A7P62_20120) 160863..161333 + 471 WP_064690735.1 type II toxin-antitoxin system YhaV family toxin Toxin
A7P62_RS20125 (A7P62_20125) 161521..163596 - 2076 WP_064690736.1 4-alpha-glucanotransferase -
A7P62_RS20130 (A7P62_20130) 163605..166007 - 2403 WP_064690737.1 maltodextrin phosphorylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..582658 582658


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-148)

Antitoxin

PrlF antitoxin

(15-113)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 18304.92 Da        Isoelectric Point: 9.2814

>T276792 WP_064690735.1 NZ_CP122321:160863-161333 [Pantoea agglomerans pv. gypsophilae]
MEDSTVINGWHVYVHPCFESQLIALTNEVELLRAKYPESYQRKATTKLLAAVFKVINSEICADPHQAKFRQGDTLGEQNK
HWFRAKFLMQYRLFFRFSEQHKTIILAWMNDAETKRAYGSKRDAYKVFSGMLHNGYPPDDWALLLKQSQDWAKINS

Download         Length: 471 bp

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12285.96 Da        Isoelectric Point: 4.3278

>AT276792 WP_033773852.1 NZ_CP122321:160512-160856 [Pantoea agglomerans pv. gypsophilae]
MGTLTHANISLRASSKLTARSQTTIPAAVRDAMNLQPGENIEYAVLPGGKVLITRQETVTDDDPVMASFLSFLAADIRNT
PANIKTLDRGLLTRITSLTEGMDVDLDAPLMDDE

Download         Length: 345 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References