Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 3557268..3557928 Replicon chromosome
Accession NZ_CP122320
Organism Pantoea agglomerans pv. gypsophilae strain 824-1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag A7P62_RS16950 Protein ID WP_033772148.1
Coordinates 3557575..3557928 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag A7P62_RS16945 Protein ID WP_010247918.1
Coordinates 3557268..3557570 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7P62_RS16925 (3553107) 3553107..3554132 - 1026 WP_174819610.1 ABC transporter permease -
A7P62_RS16930 (3554156) 3554156..3555640 - 1485 WP_010247905.1 sugar ABC transporter ATP-binding protein -
A7P62_RS16935 (3555673) 3555673..3556596 - 924 WP_010247907.1 sugar ABC transporter substrate-binding protein -
A7P62_RS16945 (3557268) 3557268..3557570 - 303 WP_010247918.1 XRE family transcriptional regulator Antitoxin
A7P62_RS16950 (3557575) 3557575..3557928 - 354 WP_033772148.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A7P62_RS16955 (3558227) 3558227..3559315 - 1089 WP_029519619.1 YncE family protein -
A7P62_RS16960 (3559711) 3559711..3561873 + 2163 WP_074399302.1 ferric-rhodotorulic acid/ferric-coprogen receptor FhuE -
A7P62_RS16965 (3561950) 3561950..3562351 - 402 WP_064690186.1 cell envelope integrity TolA C-terminal domain-containing protein -
A7P62_RS16970 (3562450) 3562450..3562731 - 282 WP_010247933.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

HigA2-like, helix-turn-helix domain

(18-89)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13681.77 Da        Isoelectric Point: 8.4949

>T276790 WP_033772148.1 NZ_CP122320:c3557928-3557575 [Pantoea agglomerans pv. gypsophilae]
VWMIKTTERFDRWFTLLNESDRACVLAALMVLREKGPGLSRPYADTLKGSVYINMKELRIQSRGDPIRAFFAFDPNRTAI
VLCAGNKMGNEKRFYQEMLPVADREFTHWLNSFKDEE

Download         Length: 354 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10941.72 Da        Isoelectric Point: 5.7251

>AT276790 WP_010247918.1 NZ_CP122320:c3557570-3557268 [Pantoea agglomerans pv. gypsophilae]
MGRTLEQLIADEKPEVVADAQAMATDILLNIHLAELREKVQKTQVEMAKALGITQPTVAGMEKPGRDLKLSTLKRYIDAA
GGKLRLVVELPDGSHYGFEV

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References