Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 2230992..2231596 Replicon chromosome
Accession NZ_CP122320
Organism Pantoea agglomerans pv. gypsophilae strain 824-1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag A7P62_RS10585 Protein ID WP_010669712.1
Coordinates 2231285..2231596 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag A7P62_RS10580 Protein ID WP_010669711.1
Coordinates 2230992..2231285 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7P62_RS10560 (2226413) 2226413..2226640 + 228 WP_010254235.1 hypothetical protein -
A7P62_RS10565 (2226970) 2226970..2228079 + 1110 WP_033779531.1 suppressor of fused domain protein -
A7P62_RS10570 (2228271) 2228271..2230166 + 1896 WP_022625996.1 methyl-accepting chemotaxis protein -
A7P62_RS10575 (2230313) 2230313..2230855 + 543 WP_064690047.1 isopentenyl-diphosphate Delta-isomerase -
A7P62_RS10580 (2230992) 2230992..2231285 - 294 WP_010669711.1 NadS family protein Antitoxin
A7P62_RS10585 (2231285) 2231285..2231596 - 312 WP_010669712.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A7P62_RS10590 (2231775) 2231775..2233250 - 1476 WP_033785500.1 MFS transporter -
A7P62_RS10595 (2233557) 2233557..2234468 + 912 WP_064690048.1 ABC transporter substrate-binding protein -
A7P62_RS10600 (2234472) 2234472..2235647 + 1176 WP_064690049.1 ABC transporter permease -
A7P62_RS10605 (2235640) 2235640..2236587 + 948 WP_010254263.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-87)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11997.67 Da        Isoelectric Point: 5.8988

>T276787 WP_010669712.1 NZ_CP122320:c2231596-2231285 [Pantoea agglomerans pv. gypsophilae]
MLFIETPVFTEDVKELLSDDEYREFQQFMADNPGWGDVIQNTGGLRKVRWAAKGKGKRGGVRVIYYYKVSESQIRLLLIY
KKGVQDDLSEDEKHLLRALNEGW

Download         Length: 312 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10741.39 Da        Isoelectric Point: 10.6798

>AT276787 WP_010669711.1 NZ_CP122320:c2231285-2230992 [Pantoea agglomerans pv. gypsophilae]
MDKKLFERLKESMTQMNEIVEGSRAPARESTVTAVKVKAIRNATGLSQSGFAKLISVNVDTLKNWEQGRREPTGPAKALL
RAIERDPQHVIPALADK

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References