Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1329499..1330144 Replicon chromosome
Accession NZ_CP122320
Organism Pantoea agglomerans pv. gypsophilae strain 824-1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag A7P62_RS06310 Protein ID WP_064690603.1
Coordinates 1329499..1329852 (+) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag A7P62_RS06315 Protein ID WP_064690602.1
Coordinates 1329845..1330144 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7P62_RS06290 (1325355) 1325355..1326320 - 966 WP_033770846.1 AraC family transcriptional regulator -
A7P62_RS06295 (1326425) 1326425..1327612 + 1188 WP_064690604.1 MFS transporter -
A7P62_RS06300 (1327825) 1327825..1328034 + 210 WP_009092571.1 DUF1471 domain-containing protein -
A7P62_RS06305 (1328237) 1328237..1329289 + 1053 WP_010672046.1 YncE family protein -
A7P62_RS06310 (1329499) 1329499..1329852 + 354 WP_064690603.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A7P62_RS06315 (1329845) 1329845..1330144 + 300 WP_064690602.1 helix-turn-helix transcriptional regulator Antitoxin
A7P62_RS06320 (1330192) 1330192..1331436 - 1245 WP_010252115.1 peptide antibiotic transporter SbmA -
A7P62_RS06325 (1331713) 1331713..1332447 + 735 WP_010672043.1 gluconate 2-dehydrogenase subunit 3 family protein -
A7P62_RS06330 (1332450) 1332450..1334234 + 1785 WP_064690601.1 GMC family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1320095..1330144 10049


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-107)

Antitoxin

Cro/C1-type helix-turn-helix domain

(31-84)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13429.33 Da        Isoelectric Point: 7.2774

>T276784 WP_064690603.1 NZ_CP122320:1329499-1329852 [Pantoea agglomerans pv. gypsophilae]
MWDVDTTKRFDEWFKAQSEELKEDMLAAIVILSEYGPHLARPFADTVDGSHFPNMKELRVQHQGKPIRAFFAFDPSRRGI
VLCAGDKTGVKEKKFYKDMIKLADAEFRKYLNGGDNG

Download         Length: 354 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11158.02 Da        Isoelectric Point: 9.6550

>AT276784 WP_064690602.1 NZ_CP122320:1329845-1330144 [Pantoea agglomerans pv. gypsophilae]
MANLKELMANQSPESRERIAKKVDAMRQVIALHMLREELNLSQTEMAYAMGVKQPTIARMEQADNDPRLSTLKRYVTALG
GEISIDVKLPTGKRIAFDL

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References