Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 1502917..1503139 Replicon chromosome
Accession NZ_CP122319
Organism Escherichia coli strain BW25113

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag QCG47_RS07200 Protein ID WP_000141634.1
Coordinates 1502917..1503024 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 1503073..1503139 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCG47_RS07175 1498170..1498898 - 729 WP_011310329.1 cellulose biosynthesis protein BcsQ -
QCG47_RS07180 1498934..1499122 - 189 WP_001063318.1 cellulose biosynthesis protein BcsR -
QCG47_RS07185 1499395..1500966 + 1572 WP_001204931.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
QCG47_RS07190 1500963..1501154 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
QCG47_RS07195 1501151..1502830 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
QCG47_RS07200 1502917..1503024 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 1503073..1503139 + 67 - - Antitoxin
QCG47_RS07205 1503500..1504771 + 1272 WP_001295225.1 aromatic amino acid transport family protein -
QCG47_RS07210 1504801..1505805 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
QCG47_RS07215 1505802..1506785 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
QCG47_RS07220 1506796..1507698 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T276754 WP_000141634.1 NZ_CP122319:c1503024-1502917 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

Antitoxin


Download         Length: 67 bp

>AT276754 NZ_CP122319:1503073-1503139 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References