Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
Location | 1673345..1674038 | Replicon | chromosome |
Accession | NZ_CP122317 | ||
Organism | Escherichia coli strain HT-948 |
Toxin (Protein)
Gene name | mqsR | Uniprot ID | S1EZG2 |
Locus tag | QCG49_RS08105 | Protein ID | WP_000415584.1 |
Coordinates | 1673742..1674038 (-) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | mqsA | Uniprot ID | S1EBV2 |
Locus tag | QCG49_RS08100 | Protein ID | WP_000650107.1 |
Coordinates | 1673345..1673740 (-) | Length | 132 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QCG49_RS08090 (1669209) | 1669209..1671467 | - | 2259 | WP_001281881.1 | DNA topoisomerase IV subunit A | - |
QCG49_RS08095 (1671605) | 1671605..1673212 | - | 1608 | WP_001295629.1 | ABC transporter substrate-binding protein | - |
QCG49_RS08100 (1673345) | 1673345..1673740 | - | 396 | WP_000650107.1 | type II toxin-antitoxin system antitoxin MqsA | Antitoxin |
QCG49_RS08105 (1673742) | 1673742..1674038 | - | 297 | WP_000415584.1 | type II toxin-antitoxin system toxin MqsR | Toxin |
QCG49_RS08110 (1674243) | 1674243..1674725 | - | 483 | WP_000183505.1 | GyrI-like domain-containing protein | - |
QCG49_RS08115 (1674778) | 1674778..1675170 | - | 393 | WP_000712658.1 | OB fold stress tolerance protein YgiW | - |
QCG49_RS08120 (1675322) | 1675322..1675981 | + | 660 | WP_001221495.1 | quorum sensing response regulator transcription factor QseB | - |
QCG49_RS08125 (1675978) | 1675978..1677327 | + | 1350 | WP_000673402.1 | quorum sensing histidine kinase QseC | - |
QCG49_RS08130 (1677373) | 1677373..1677705 | - | 333 | WP_000917684.1 | DUF2645 family protein | - |
QCG49_RS08135 (1678024) | 1678024..1678605 | + | 582 | WP_000065430.1 | NADPH:quinone oxidoreductase MdaB | - |
QCG49_RS08140 (1678636) | 1678636..1678950 | + | 315 | WP_000958598.1 | putative quinol monooxygenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11231.96 Da Isoelectric Point: 8.9070
>T276699 WP_000415584.1 NZ_CP122317:c1674038-1673742 [Escherichia coli]
MEKRTPHTRLSQVKKLVNAGQVRTTRSALLNADELGLDFDGMCNVIIGLSESDFYKSMTTYSDHTIWQDVYRPRLVTGQV
YLKITVIHDVLIVSFKEK
MEKRTPHTRLSQVKKLVNAGQVRTTRSALLNADELGLDFDGMCNVIIGLSESDFYKSMTTYSDHTIWQDVYRPRLVTGQV
YLKITVIHDVLIVSFKEK
Download Length: 297 bp
Antitoxin
Download Length: 132 a.a. Molecular weight: 14703.10 Da Isoelectric Point: 9.2136
>AT276699 WP_000650107.1 NZ_CP122317:c1673740-1673345 [Escherichia coli]
MKCPVCHQGEMVSGIKDIPYTFRGRKTVLKGIHGLYCVHCEESIMNKEESDAFMAQVKAFRASVNAETVAPEFIVKVRKK
LSLTQKEASEIFGGGVNAFSRYEKGNAQPHPSTIKLLRVLDKHPELLNEIR
MKCPVCHQGEMVSGIKDIPYTFRGRKTVLKGIHGLYCVHCEESIMNKEESDAFMAQVKAFRASVNAETVAPEFIVKVRKK
LSLTQKEASEIFGGGVNAFSRYEKGNAQPHPSTIKLLRVLDKHPELLNEIR
Download Length: 396 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|