Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3813207..3813429 Replicon chromosome
Accession NZ_CP122316
Organism Escherichia coli strain HT-946

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag QCG48_RS18725 Protein ID WP_000141634.1
Coordinates 3813322..3813429 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3813207..3813273 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCG48_RS18705 3808648..3809550 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
QCG48_RS18710 3809561..3810544 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
QCG48_RS18715 3810541..3811545 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
QCG48_RS18720 3811575..3812846 - 1272 WP_001295225.1 aromatic amino acid transport family protein -
- 3813207..3813273 - 67 - - Antitoxin
QCG48_RS18725 3813322..3813429 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
QCG48_RS18730 3813516..3815195 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
QCG48_RS18735 3815192..3815383 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
QCG48_RS18740 3815380..3816951 - 1572 WP_001204931.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
QCG48_RS18745 3817224..3817412 + 189 WP_001063318.1 cellulose biosynthesis protein BcsR -
QCG48_RS18750 3817448..3818176 + 729 WP_011310329.1 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T276680 WP_000141634.1 NZ_CP122316:3813322-3813429 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T276680 NZ_CP122316:3813322-3813429 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT276680 NZ_CP122316:c3813273-3813207 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References