Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 482068..482718 Replicon chromosome
Accession NZ_CP121768
Organism Glaesserella parasuis strain d76

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QBK97_RS02535 Protein ID WP_062923967.1
Coordinates 482380..482718 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QBK97_RS02530 Protein ID WP_005710405.1
Coordinates 482068..482376 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QBK97_RS02510 (QBK97_02510) 478542..479030 - 489 WP_035496521.1 transcription elongation factor GreB -
QBK97_RS02515 (QBK97_02515) 479030..479965 - 936 WP_005710401.1 KpsF/GutQ family sugar-phosphate isomerase -
QBK97_RS02520 (QBK97_02520) 480026..480607 - 582 WP_035496524.1 type IV pilus biogenesis/stability protein PilW -
QBK97_RS02525 (QBK97_02525) 480707..481867 - 1161 WP_010786053.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
QBK97_RS02530 (QBK97_02530) 482068..482376 - 309 WP_005710405.1 helix-turn-helix domain-containing protein Antitoxin
QBK97_RS02535 (QBK97_02535) 482380..482718 - 339 WP_062923967.1 toxin Toxin
QBK97_RS02560 (QBK97_02560) 483557..484996 + 1440 WP_035496906.1 glutamate--tRNA ligase -
QBK97_RS02570 (QBK97_02570) 485463..485729 - 267 Protein_478 cation-transporting ATPase PacS -
QBK97_RS02575 (QBK97_02575) 485684..486605 - 922 Protein_479 IS256 family transposase -
QBK97_RS02580 (QBK97_02580) 486726..487100 - 375 WP_035496549.1 cytochrome b562 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 486066..486605 539


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-86)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13244.26 Da        Isoelectric Point: 9.8649

>T276557 WP_062923967.1 NZ_CP121768:c482718-482380 [Glaesserella parasuis]
MNVAFVELPPFEEYRKKYLDDDTFRLLQNELLKFPDKGELIQGTGGLRKLRIVDIIRQKGKRGGARVIYYYYVQGKQVWL
FHAYNKNQQDDLSNEERVVLANTLSYLKSLVR

Download         Length: 339 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11539.61 Da        Isoelectric Point: 10.2919

>AT276557 WP_005710405.1 NZ_CP121768:c482376-482068 [Glaesserella parasuis]
MGKLFNELMEGMQALELHLQGKITLKTTVVEVPDPIVITPEEVKAIRQKLNLSQAVFARKLHTSVRTYQGWEQGRTKPNP
QAVLLLKMVEKSPKTFEQIASI

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References