Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 5635918..5636508 Replicon chromosome
Accession NZ_CP121700
Organism Methylobacterium indicum strain JDJ13

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QBE04_RS26145 Protein ID WP_279357320.1
Coordinates 5636197..5636508 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A0J6ULD8
Locus tag QBE04_RS26140 Protein ID WP_048430593.1
Coordinates 5635918..5636181 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QBE04_RS26135 5633098..5635617 + 2520 WP_279357319.1 glycogen/starch/alpha-glucan phosphorylase -
QBE04_RS26140 5635918..5636181 + 264 WP_048430593.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QBE04_RS26145 5636197..5636508 + 312 WP_279357320.1 Txe/YoeB family addiction module toxin Toxin
QBE04_RS26150 5636631..5638190 - 1560 WP_279357321.1 glucan biosynthesis protein D -
QBE04_RS26155 5638204..5638383 - 180 WP_048430596.1 hypothetical protein -
QBE04_RS26160 5638647..5640245 + 1599 WP_279357322.1 gamma-glutamyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11965.39 Da        Isoelectric Point: 7.8825

>T276545 WP_279357320.1 NZ_CP121700:5636197-5636508 [Methylobacterium indicum]
MTLTFSDDAWSDYVFWQGENTATLERINALIKEIKRTPFTGTGKPEPLKFKLKGWWSRRISGEHRLVYRVSGSGSTHTLE
IAQCRWHYDDESDSRSPCNREAL

Download         Length: 312 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9948.31 Da        Isoelectric Point: 5.1273

>AT276545 WP_048430593.1 NZ_CP121700:5635918-5636181 [Methylobacterium indicum]
MTHVSLTDFRQSIAAHFDRVERDREELVVTRQGHEPLVLLPLAELESLRETLHLLGTPANARRLMRSIEQLDAGQTIERA
LIEPDQP

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0J6ULD8

References