Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2910674..2911209 Replicon chromosome
Accession NZ_CP121682
Organism Streptomyces sp. HUAS 5

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PYS65_RS13035 Protein ID WP_279334128.1
Coordinates 2910674..2910928 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PYS65_RS13040 Protein ID WP_279334129.1
Coordinates 2910925..2911209 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYS65_RS13015 (PYS65_13015) 2906683..2907588 - 906 WP_279334124.1 sulfate adenylyltransferase subunit CysD -
PYS65_RS13020 (PYS65_13020) 2908059..2908940 + 882 WP_279334125.1 shikimate dehydrogenase -
PYS65_RS13025 (PYS65_13025) 2908957..2909691 - 735 WP_279334126.1 siderophore-interacting protein -
PYS65_RS13030 (PYS65_13030) 2909922..2910200 - 279 WP_279334127.1 hypothetical protein -
PYS65_RS13035 (PYS65_13035) 2910674..2910928 - 255 WP_279334128.1 Txe/YoeB family addiction module toxin Toxin
PYS65_RS13040 (PYS65_13040) 2910925..2911209 - 285 WP_279334129.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PYS65_RS13045 (PYS65_13045) 2911633..2912046 - 414 WP_279334130.1 PIN domain-containing protein -
PYS65_RS13050 (PYS65_13050) 2912028..2912312 - 285 WP_279334131.1 hypothetical protein -
PYS65_RS13055 (PYS65_13055) 2912863..2915235 - 2373 WP_279334132.1 2OG-Fe(II) oxygenase -
PYS65_RS13060 (PYS65_13060) 2915569..2915835 + 267 WP_109376801.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-65)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10127.61 Da        Isoelectric Point: 8.4534

>T276530 WP_279334128.1 NZ_CP121682:c2910928-2910674 [Streptomyces sp. HUAS 5]
VRLVFEDQGWEDYTSWLRSDRKMLARINRLIEDVKRDPFTGIGKPEPLKYHLPGAWSRRIDDEHRLVYLVTDKEIVILAA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10205.45 Da        Isoelectric Point: 4.8550

>AT276530 WP_279334129.1 NZ_CP121682:c2911209-2910925 [Streptomyces sp. HUAS 5]
MSITASEARKALFPLIKKVNDNHEAIEIVSKHGNAVLISAEDYAALREGSYLLRSPANARRLLKAYENALANINVSEREL
IDPDSPDAASEGAE

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References