Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 6964485..6965084 Replicon chromosome
Accession NZ_CP121668
Organism Bradyrhizobium sp. CB2312

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag QA642_RS33980 Protein ID WP_283080780.1
Coordinates 6964485..6964766 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag QA642_RS33985 Protein ID WP_283080781.1
Coordinates 6964779..6965084 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA642_RS33955 (QA642_33955) 6960561..6961442 + 882 WP_283080776.1 alpha/beta hydrolase -
QA642_RS33960 (QA642_33960) 6961680..6962624 + 945 WP_283080777.1 metallophosphoesterase -
QA642_RS33965 (QA642_33965) 6962649..6962987 + 339 WP_235539447.1 cupredoxin family copper-binding protein -
QA642_RS33970 (QA642_33970) 6963103..6963651 + 549 WP_283080778.1 sigma-70 family RNA polymerase sigma factor -
QA642_RS33975 (QA642_33975) 6963648..6964415 + 768 WP_283080779.1 anti-sigma factor -
QA642_RS33980 (QA642_33980) 6964485..6964766 + 282 WP_283080780.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QA642_RS33985 (QA642_33985) 6964779..6965084 + 306 WP_283080781.1 HigA family addiction module antitoxin Antitoxin
QA642_RS33990 (QA642_33990) 6965109..6965513 - 405 WP_283080782.1 GFA family protein -
QA642_RS33995 (QA642_33995) 6965631..6967022 - 1392 WP_283080783.1 aminobacteriohopanetriol synthase HpnO -
QA642_RS34000 (QA642_34000) 6967163..6967786 + 624 WP_283080784.1 DUF2147 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(2-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(5-83)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10473.92 Da        Isoelectric Point: 9.0512

>T276522 WP_283080780.1 NZ_CP121668:6964485-6964766 [Bradyrhizobium sp. CB2312]
VIRTFRDKTTEAVFNGESPKGFPADLVKVARRKLRYLHAAAELGDLRAPPGNRLEALAGDRKGQHSIRINDQFRVCFIWT
AEGPAEVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11093.97 Da        Isoelectric Point: 10.3127

>AT276522 WP_283080781.1 NZ_CP121668:6964779-6965084 [Bradyrhizobium sp. CB2312]
MARKLKPMHPGEVLREEFLIPLNMSAGALAKTCGLPRTRLERIASEQTGITADTALRLGKALGTTAELWLNLQNDFDIQI
AKRDLGKALDRIETVNKPKAA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References