Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 3320690..3321215 Replicon chromosome
Accession NZ_CP121662
Organism Rhizobium sp. CB3090

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QA646_RS15970 Protein ID WP_283056392.1
Coordinates 3320943..3321215 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QA646_RS15965 Protein ID WP_283056391.1
Coordinates 3320690..3320941 (+) Length 84 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA646_RS15950 (QA646_15950) 3316428..3318071 + 1644 WP_283056389.1 thiamine/thiamine pyrophosphate ABC transporter permease ThiP -
QA646_RS15955 (QA646_15955) 3318061..3318789 + 729 WP_283056390.1 ATP-binding cassette domain-containing protein -
QA646_RS15960 (QA646_15960) 3319132..3320592 + 1461 WP_283058890.1 M48 family metalloprotease -
QA646_RS15965 (QA646_15965) 3320690..3320941 + 252 WP_283056391.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QA646_RS15970 (QA646_15970) 3320943..3321215 + 273 WP_283056392.1 Txe/YoeB family addiction module toxin Toxin
QA646_RS15975 (QA646_15975) 3321299..3322162 - 864 WP_283056393.1 RNA polymerase factor sigma-32 -
QA646_RS15980 (QA646_15980) 3322574..3323146 - 573 WP_107109815.1 CarD family transcriptional regulator -
QA646_RS15985 (QA646_15985) 3323547..3323885 - 339 WP_107109816.1 ferredoxin family protein -
QA646_RS15990 (QA646_15990) 3324093..3324497 - 405 WP_283056394.1 RNA-binding S4 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-88)

Antitoxin

(1-72)


Sequences


Toxin        


Download         Length: 91 a.a.        Molecular weight: 10767.41 Da        Isoelectric Point: 9.7419

>T276516 WP_283056392.1 NZ_CP121662:3320943-3321215 [Rhizobium sp. CB3090]
MKLLWTPNSWEEYEYWQKNDQKMVEKINELLKDVKRSPFKGLGKPEPLKGDLSGFWSRRILGERRLVYCVTGKGSSQQSE
IIQCRFHYEK

Download         Length: 273 bp


Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9359.66 Da        Isoelectric Point: 4.9902

>AT276516 WP_283056391.1 NZ_CP121662:3320690-3320941 [Rhizobium sp. CB3090]
MAHVRLTEFLQNIATYFDQVLSSRAPLLVTRQGSEAMVLIAESEYESMQETLHLLSTPANSARLRDSIQQLRKGQLIESD
PTL

Download         Length: 252 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References