Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1705394..1705986 Replicon chromosome
Accession NZ_CP121652
Organism Rhizobium sp. CB3171

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QA648_RS08385 Protein ID WP_104823382.1
Coordinates 1705705..1705986 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag QA648_RS08380 Protein ID WP_283050820.1
Coordinates 1705394..1705693 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA648_RS08370 (QA648_08370) 1701003..1701602 - 600 WP_283050816.1 dimethylsulfonioproprionate lyase family protein -
QA648_RS08375 (QA648_08375) 1701599..1705369 - 3771 WP_283050818.1 cobaltochelatase subunit CobN -
QA648_RS08380 (QA648_08380) 1705394..1705693 - 300 WP_283050820.1 HigA family addiction module antitoxin Antitoxin
QA648_RS08385 (QA648_08385) 1705705..1705986 - 282 WP_104823382.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QA648_RS08390 (QA648_08390) 1706044..1707093 - 1050 WP_283050823.1 cobalamin biosynthesis protein CobW -
QA648_RS08395 (QA648_08395) 1707099..1707626 - 528 WP_283050825.1 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase -
QA648_RS08400 (QA648_08400) 1708349..1710145 + 1797 WP_283050827.1 chloride channel protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(16-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-97)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10517.96 Da        Isoelectric Point: 8.9312

>T276493 WP_104823382.1 NZ_CP121652:c1705986-1705705 [Rhizobium sp. CB3171]
VIVSYKGKFAEAVASGNVPKGFPADLVRSAQRKLTILNYAVVLDDLRSPPGNRLERLQGDRSGQYSIRINDQWRICFLWT
EAGPRDVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10958.67 Da        Isoelectric Point: 5.7011

>AT276493 WP_283050820.1 NZ_CP121652:c1705693-1705394 [Rhizobium sp. CB3171]
MTETKLPPIHPGEILREEYLKPLTMSAGALAKHLNVPRTRIERLVSEETGVTADTALRLARFFSTTPDFWMAMQTGYDLA
IAQAEKSDVFAAIKPLEAA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References