Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 6045825..6046424 Replicon chromosome
Accession NZ_CP121650
Organism Bradyrhizobium sp. CB82

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag QA640_RS29480 Protein ID WP_283036372.1
Coordinates 6045825..6046106 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag QA640_RS29485 Protein ID WP_283036373.1
Coordinates 6046119..6046424 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA640_RS29450 (QA640_29450) 6040938..6042128 - 1191 WP_283036367.1 efflux RND transporter periplasmic adaptor subunit -
QA640_RS29455 (QA640_29455) 6042135..6042446 + 312 WP_283036368.1 hypothetical protein -
QA640_RS29460 (QA640_29460) 6043055..6043993 + 939 WP_283036369.1 metallophosphoesterase -
QA640_RS29465 (QA640_29465) 6044007..6044330 + 324 WP_283036370.1 cupredoxin family copper-binding protein -
QA640_RS29470 (QA640_29470) 6044434..6044976 + 543 WP_283042922.1 sigma-70 family RNA polymerase sigma factor -
QA640_RS29475 (QA640_29475) 6044982..6045743 + 762 WP_283036371.1 anti-sigma factor -
QA640_RS29480 (QA640_29480) 6045825..6046106 + 282 WP_283036372.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QA640_RS29485 (QA640_29485) 6046119..6046424 + 306 WP_283036373.1 HigA family addiction module antitoxin Antitoxin
QA640_RS29490 (QA640_29490) 6046502..6047893 - 1392 WP_283036374.1 aminobacteriohopanetriol synthase HpnO -
QA640_RS29495 (QA640_29495) 6048018..6048632 + 615 WP_283036375.1 DUF2147 domain-containing protein -
QA640_RS29500 (QA640_29500) 6048600..6051188 - 2589 WP_283036376.1 MMPL family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-100)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10557.96 Da        Isoelectric Point: 9.8495

>T276488 WP_283036372.1 NZ_CP121650:6045825-6046106 [Bradyrhizobium sp. CB82]
VIRTFRDRATEAVFNGEAPKGFPADLVKVARRKLRYLHAADNLSDLRSPPGNRLEALAGNRRGQHSIRINDQFRICFVWT
AEGPAEVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11062.94 Da        Isoelectric Point: 10.3434

>AT276488 WP_283036373.1 NZ_CP121650:6046119-6046424 [Bradyrhizobium sp. CB82]
MAKKLKPMHPGEVLREEFLVPLNTSAGALAKACGLPRTRIERIASEQTGITADTALRLAKALGTTAQLWLNLQNDYDIQI
AKRELGKVLDRIETVNKPKAA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References