Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 7999353..7999966 Replicon chromosome
Accession NZ_CP121647
Organism Bradyrhizobium sp. CB3481

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QA643_RS38480 Protein ID WP_283031124.1
Coordinates 7999670..7999966 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QA643_RS38475 Protein ID WP_283031122.1
Coordinates 7999353..7999661 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA643_RS38450 (QA643_38450) 7994449..7996383 - 1935 WP_283031114.1 cyclic nucleotide-binding domain-containing protein -
QA643_RS38455 (QA643_38455) 7996532..7997611 - 1080 WP_283031116.1 LLM class flavin-dependent oxidoreductase -
QA643_RS38460 (QA643_38460) 7997748..7998155 + 408 WP_283031118.1 YccF domain-containing protein -
QA643_RS38465 (QA643_38465) 7998168..7998641 - 474 WP_283031120.1 universal stress protein -
QA643_RS38475 (QA643_38475) 7999353..7999661 - 309 WP_283031122.1 HigA family addiction module antitoxin Antitoxin
QA643_RS38480 (QA643_38480) 7999670..7999966 - 297 WP_283031124.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QA643_RS38485 (QA643_38485) 8000106..8000636 + 531 WP_283031126.1 bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase -
QA643_RS38490 (QA643_38490) 8000777..8000983 - 207 WP_283031128.1 hypothetical protein -
QA643_RS38495 (QA643_38495) 8001502..8002002 - 501 WP_283031130.1 copper chaperone PCu(A)C -
QA643_RS38500 (QA643_38500) 8002324..8003475 + 1152 WP_283031132.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-95)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(3-94)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11749.15 Da        Isoelectric Point: 7.4034

>T276486 WP_283031124.1 NZ_CP121647:c7999966-7999670 [Bradyrhizobium sp. CB3481]
MISNFRDDWLRAFFVDDVHSRNVPPDLESRLFRKLQMLDDATTDQDLRVPPSNHFEKLRGKLEGFHSIRVNSQWRLIFRW
DGRRGEASGVYLDDHSYR

Download         Length: 297 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11556.50 Da        Isoelectric Point: 11.4325

>AT276486 WP_283031122.1 NZ_CP121647:c7999661-7999353 [Bradyrhizobium sp. CB3481]
MLMTKRKPATVGEILAQEFMEPMSLTQSALAKAMGVQRKHVNELCNDRRAITAPTALILARVFGNSPDFWLNVQRRSDIW
EAMHSPRERERIKRARPIGAAA

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References