Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 3419535..3420143 Replicon chromosome
Accession NZ_CP121647
Organism Bradyrhizobium sp. CB3481

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag QA643_RS16490 Protein ID WP_283034825.1
Coordinates 3419535..3419819 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QA643_RS16495 Protein ID WP_283034152.1
Coordinates 3419832..3420143 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QA643_RS16465 (QA643_16465) 3415410..3416120 + 711 WP_283034147.1 tetratricopeptide repeat protein -
QA643_RS16470 (QA643_16470) 3416139..3416972 - 834 WP_283034148.1 class I SAM-dependent methyltransferase -
QA643_RS16475 (QA643_16475) 3417118..3417717 - 600 WP_283034149.1 TetR/AcrR family transcriptional regulator -
QA643_RS16480 (QA643_16480) 3417887..3418264 + 378 WP_283034150.1 tautomerase family protein -
QA643_RS16485 (QA643_16485) 3418413..3419354 - 942 WP_283034151.1 alpha/beta hydrolase -
QA643_RS16490 (QA643_16490) 3419535..3419819 + 285 WP_283034825.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QA643_RS16495 (QA643_16495) 3419832..3420143 + 312 WP_283034152.1 HigA family addiction module antitoxin Antitoxin
QA643_RS16500 (QA643_16500) 3420150..3421367 + 1218 WP_283034153.1 RluA family pseudouridine synthase -
QA643_RS16505 (QA643_16505) 3421465..3422679 + 1215 WP_283034154.1 amidohydrolase family protein -
QA643_RS16510 (QA643_16510) 3422838..3423611 + 774 WP_283034155.1 ATP12 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-55)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10698.08 Da        Isoelectric Point: 7.1660

>T276482 WP_283034825.1 NZ_CP121647:3419535-3419819 [Bradyrhizobium sp. CB3481]
MIVSYRDKRTERFASGRHVKEFSGFARQAEMRLDRLDAATSLADLAALPGNRLEALRGDRAGLYSIRINDQWRICFAWPE
GSSGPIEVEIVDYH

Download         Length: 285 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11431.93 Da        Isoelectric Point: 7.4052

>AT276482 WP_283034152.1 NZ_CP121647:3419832-3420143 [Bradyrhizobium sp. CB3481]
MPRSPIHPGEHLAEELNELGITAAELSRQIDVPVNRITGIIHGQRGITADTALRLGHWFGNSPQFWMNLQQLYELRLAEN
EVGAEIAALPRRAGRTASRQGRS

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References