Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 6553..7211 Replicon plasmid pIV_MAB9
Accession NZ_CP121589
Organism Acinetobacter baumannii strain MAB9

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag MTS46_RS19670 Protein ID WP_000312250.1
Coordinates 6553..6912 (+) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag MTS46_RS19675 Protein ID WP_001096429.1
Coordinates 6912..7211 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS46_RS19640 (MTS46_19640) 2074..2388 - 315 WP_000708714.1 hypothetical protein -
MTS46_RS19645 (MTS46_19645) 3443..4201 - 759 WP_001053127.1 hypothetical protein -
MTS46_RS19650 (MTS46_19650) 4268..4651 - 384 WP_000654348.1 hypothetical protein -
MTS46_RS19655 (MTS46_19655) 4790..5488 - 699 WP_000873188.1 hypothetical protein -
MTS46_RS19660 (MTS46_19660) 5555..5737 - 183 WP_000373385.1 hypothetical protein -
MTS46_RS19665 (MTS46_19665) 5786..6352 - 567 WP_000710385.1 hypothetical protein -
MTS46_RS19670 (MTS46_19670) 6553..6912 + 360 WP_000312250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MTS46_RS19675 (MTS46_19675) 6912..7211 + 300 WP_001096429.1 XRE family transcriptional regulator Antitoxin
MTS46_RS19680 (MTS46_19680) 7749..8285 - 537 WP_000731978.1 hypothetical protein -
MTS46_RS19685 (MTS46_19685) 8335..8889 - 555 WP_000790084.1 hypothetical protein -
MTS46_RS19690 (MTS46_19690) 8909..9127 - 219 WP_001043201.1 hypothetical protein -
MTS46_RS19695 (MTS46_19695) 9167..9796 - 630 WP_000701003.1 hypothetical protein -
MTS46_RS19700 (MTS46_19700) 9813..9992 - 180 WP_000387630.1 hypothetical protein -
MTS46_RS19705 (MTS46_19705) 9968..10540 - 573 WP_000443897.1 hypothetical protein -
MTS46_RS19710 (MTS46_19710) 10545..10802 - 258 WP_000834290.1 hypothetical protein -
MTS46_RS19715 (MTS46_19715) 10907..12187 - 1281 WP_001093570.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..68108 68108


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-88)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13751.62 Da        Isoelectric Point: 4.8212

>T276439 WP_000312250.1 NZ_CP121589:6553-6912 [Acinetobacter baumannii]
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK

Download         Length: 360 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11012.93 Da        Isoelectric Point: 10.4856

>AT276439 WP_001096429.1 NZ_CP121589:6912-7211 [Acinetobacter baumannii]
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References