Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 58844..59502 Replicon plasmid pIV_RAB73
Accession NZ_CP121568
Organism Acinetobacter baumannii strain RAB73

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag MTS81_RS19305 Protein ID WP_000312250.1
Coordinates 59143..59502 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag MTS81_RS19300 Protein ID WP_001096429.1
Coordinates 58844..59143 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS81_RS19260 (MTS81_19260) 53870..55150 + 1281 WP_001093570.1 hypothetical protein -
MTS81_RS19265 (MTS81_19265) 55255..55512 + 258 WP_000834290.1 hypothetical protein -
MTS81_RS19270 (MTS81_19270) 55517..56089 + 573 WP_000443897.1 hypothetical protein -
MTS81_RS19275 (MTS81_19275) 56065..56244 + 180 WP_000387630.1 hypothetical protein -
MTS81_RS19280 (MTS81_19280) 56261..56890 + 630 WP_000701003.1 hypothetical protein -
MTS81_RS19285 (MTS81_19285) 56930..57148 + 219 WP_001043201.1 hypothetical protein -
MTS81_RS19290 (MTS81_19290) 57168..57722 + 555 WP_000790084.1 hypothetical protein -
MTS81_RS19295 (MTS81_19295) 57772..58308 + 537 WP_000731978.1 hypothetical protein -
MTS81_RS19300 (MTS81_19300) 58844..59143 - 300 WP_001096429.1 XRE family transcriptional regulator Antitoxin
MTS81_RS19305 (MTS81_19305) 59143..59502 - 360 WP_000312250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MTS81_RS19310 (MTS81_19310) 59703..60269 + 567 WP_000710385.1 hypothetical protein -
MTS81_RS19315 (MTS81_19315) 60318..60500 + 183 WP_000373385.1 hypothetical protein -
MTS81_RS19320 (MTS81_19320) 60567..61265 + 699 WP_000873188.1 hypothetical protein -
MTS81_RS19325 (MTS81_19325) 61404..61787 + 384 WP_000654348.1 hypothetical protein -
MTS81_RS19330 (MTS81_19330) 61854..62612 + 759 WP_001053127.1 hypothetical protein -
MTS81_RS19335 (MTS81_19335) 63661..63975 + 315 WP_000708714.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..68038 68038


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-88)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13751.62 Da        Isoelectric Point: 4.8212

>T276422 WP_000312250.1 NZ_CP121568:c59502-59143 [Acinetobacter baumannii]
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK

Download         Length: 360 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11012.93 Da        Isoelectric Point: 10.4856

>AT276422 WP_001096429.1 NZ_CP121568:c59143-58844 [Acinetobacter baumannii]
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References