Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 42974..43632 Replicon plasmid pIV_RAB94
Accession NZ_CP121564
Organism Acinetobacter baumannii strain RAB94

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag MTS31_RS19305 Protein ID WP_000312250.1
Coordinates 42974..43333 (+) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag MTS31_RS19310 Protein ID WP_001096429.1
Coordinates 43333..43632 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS31_RS19275 (MTS31_19275) 38495..38809 - 315 WP_000708714.1 hypothetical protein -
MTS31_RS19280 (MTS31_19280) 39864..40622 - 759 WP_001053127.1 hypothetical protein -
MTS31_RS19285 (MTS31_19285) 40689..41072 - 384 WP_000654348.1 hypothetical protein -
MTS31_RS19290 (MTS31_19290) 41211..41909 - 699 WP_000873188.1 hypothetical protein -
MTS31_RS19295 (MTS31_19295) 41976..42158 - 183 WP_000373385.1 hypothetical protein -
MTS31_RS19300 (MTS31_19300) 42207..42773 - 567 WP_000710385.1 hypothetical protein -
MTS31_RS19305 (MTS31_19305) 42974..43333 + 360 WP_000312250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MTS31_RS19310 (MTS31_19310) 43333..43632 + 300 WP_001096429.1 XRE family transcriptional regulator Antitoxin
MTS31_RS19315 (MTS31_19315) 44170..44706 - 537 WP_000731978.1 hypothetical protein -
MTS31_RS19320 (MTS31_19320) 44756..45310 - 555 WP_000790084.1 hypothetical protein -
MTS31_RS19325 (MTS31_19325) 45330..45548 - 219 WP_001043201.1 hypothetical protein -
MTS31_RS19330 (MTS31_19330) 45588..46217 - 630 WP_000701003.1 hypothetical protein -
MTS31_RS19335 (MTS31_19335) 46234..46413 - 180 WP_000387630.1 hypothetical protein -
MTS31_RS19340 (MTS31_19340) 46389..46961 - 573 WP_000443897.1 hypothetical protein -
MTS31_RS19345 (MTS31_19345) 46966..47223 - 258 WP_000834290.1 hypothetical protein -
MTS31_RS19350 (MTS31_19350) 47328..48608 - 1281 WP_001093570.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid aph(3')-VIa - 1..70111 70111


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-88)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13751.62 Da        Isoelectric Point: 4.8212

>T276420 WP_000312250.1 NZ_CP121564:42974-43333 [Acinetobacter baumannii]
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK

Download         Length: 360 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11012.93 Da        Isoelectric Point: 10.4856

>AT276420 WP_001096429.1 NZ_CP121564:43333-43632 [Acinetobacter baumannii]
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References