276416

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 35863..36521 Replicon plasmid pIV_RAB97
Accession NZ_CP121561
Organism Acinetobacter baumannii strain RAB97

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag MTS88_RS19850 Protein ID WP_000312250.1
Coordinates 35863..36222 (+) Length 120 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag MTS88_RS19855 Protein ID WP_001096429.1
Coordinates 36222..36521 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTS88_RS19820 (MTS88_19820) 31384..31698 - 315 WP_000708714.1 hypothetical protein -
MTS88_RS19825 (MTS88_19825) 32753..33511 - 759 WP_001053127.1 hypothetical protein -
MTS88_RS19830 (MTS88_19830) 33578..33961 - 384 WP_000654348.1 hypothetical protein -
MTS88_RS19835 (MTS88_19835) 34100..34798 - 699 WP_000873188.1 hypothetical protein -
MTS88_RS19840 (MTS88_19840) 34865..35047 - 183 WP_000373385.1 hypothetical protein -
MTS88_RS19845 (MTS88_19845) 35096..35662 - 567 WP_000710385.1 hypothetical protein -
MTS88_RS19850 (MTS88_19850) 35863..36222 + 360 WP_000312250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MTS88_RS19855 (MTS88_19855) 36222..36521 + 300 WP_001096429.1 XRE family transcriptional regulator Antitoxin
MTS88_RS19860 (MTS88_19860) 37059..37595 - 537 WP_000731978.1 hypothetical protein -
MTS88_RS19865 (MTS88_19865) 37645..38199 - 555 WP_000790084.1 hypothetical protein -
MTS88_RS19870 (MTS88_19870) 38219..38437 - 219 WP_001043201.1 hypothetical protein -
MTS88_RS19875 (MTS88_19875) 38477..39106 - 630 WP_000701003.1 hypothetical protein -
MTS88_RS19880 (MTS88_19880) 39123..39302 - 180 WP_000387630.1 hypothetical protein -
MTS88_RS19885 (MTS88_19885) 39278..39850 - 573 WP_000443897.1 hypothetical protein -
MTS88_RS19890 (MTS88_19890) 39855..40112 - 258 WP_000834290.1 hypothetical protein -
MTS88_RS19895 (MTS88_19895) 40217..41497 - 1281 WP_001093570.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..68813 68813


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-109)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-88)


Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13751.62 Da        Isoelectric Point: 4.8212

>T276416 WP_000312250.1 NZ_CP121561:35863-36222 [Acinetobacter baumannii]
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK

Download         Length: 360 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11012.93 Da        Isoelectric Point: 10.4856

>AT276416 WP_001096429.1 NZ_CP121561:36222-36521 [Acinetobacter baumannii]
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References