Detailed information of TA system TA276370

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/Fst(toxin)
• Location: 7416..7576
• Replicon: plasmid unnamed2
• Accession: NZ_CP121488
• Organism: Staphylococcus epidermidis strain 32FSE02

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: QA591_RS11820
• Protein ID: WP_152901349.1
• Coordinates: 7481..7576 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	7416..7453 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QA591_RS11815 (6420)	6420..7022	-	603	WP_049366465.1	recombinase family protein	-
- (7416)	7416..7453	+	38	NuclAT_0	-	Antitoxin
- (7416)	7416..7453	+	38	NuclAT_0	-	Antitoxin
QA591_RS11820 (7481)	7481..7576	-	96	WP_152901349.1	type I toxin-antitoxin system Fst family toxin	Toxin
QA591_RS11825 (7941)	7941..9194	-	1254	WP_080351652.1	replication initiator protein A	-
QA591_RS11830 (9830)	9830..10624	+	795	WP_049366491.1	ParA family protein	-
QA591_RS11835 (10630)	10630..10830	+	201	WP_002485209.1	hypothetical protein	-
QA591_RS11840 (11052)	11052..11881	-	830	Protein_7	RepB family plasmid replication initiator protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3587.36 Da
• Isoelectric Point: 9.9256

>T276370 WP_152901349.1 NZ_CP121488:c7576-7481 [Staphylococcus epidermidis]
MLMIFVHIIAPVISGCAVAYFTYWLNSKRNK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 38 bp

>AT276370 NZ_CP121488:7416-7453 [Staphylococcus epidermidis]
TATGCACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin