Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2906338..2907038 Replicon chromosome
Accession NZ_CP121476
Organism Pseudomonas sp. 905_Psudmo1

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag P9K38_RS13640 Protein ID WP_278324856.1
Coordinates 2906742..2907038 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A1H2LFQ3
Locus tag P9K38_RS13635 Protein ID WP_031306592.1
Coordinates 2906338..2906739 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9K38_RS13615 (P9K38_13615) 2901796..2903154 - 1359 WP_196448421.1 glutathione-disulfide reductase -
P9K38_RS13620 (P9K38_13620) 2903227..2903649 + 423 WP_059391986.1 VOC family protein -
P9K38_RS13625 (P9K38_13625) 2903786..2904625 - 840 WP_003460169.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
P9K38_RS13630 (P9K38_13630) 2904668..2906029 - 1362 WP_278326893.1 UDP-glucose/GDP-mannose dehydrogenase family protein -
P9K38_RS13635 (P9K38_13635) 2906338..2906739 - 402 WP_031306592.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
P9K38_RS13640 (P9K38_13640) 2906742..2907038 - 297 WP_278324856.1 type II toxin-antitoxin system MqsR family toxin Toxin
P9K38_RS13650 (P9K38_13650) 2907523..2907741 - 219 WP_021489012.1 hypothetical protein -
P9K38_RS13655 (P9K38_13655) 2907928..2908617 + 690 WP_003460095.1 crotonase/enoyl-CoA hydratase family protein -
P9K38_RS13660 (P9K38_13660) 2908738..2909121 - 384 WP_230924410.1 hypothetical protein -
P9K38_RS13665 (P9K38_13665) 2909285..2909599 + 315 WP_012018520.1 hypothetical protein -
P9K38_RS13670 (P9K38_13670) 2909986..2911269 + 1284 WP_112210028.1 CmpA/NrtA family ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(3-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11384.25 Da        Isoelectric Point: 8.3837

>T276352 WP_278324856.1 NZ_CP121476:c2907038-2906742 [Pseudomonas sp. 905_Psudmo1]
MKKRKPYFKLELVKQAVTEQRYRFTRVALEGGAELGMEMADMLAVISALSSRDFFKSMTTYADHTTWQDVYLPDTEFGQV
YLKFTLVADLLIVSFKEK

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14781.69 Da        Isoelectric Point: 6.4554

>AT276352 WP_031306592.1 NZ_CP121476:c2906739-2906338 [Pseudomonas sp. 905_Psudmo1]
MKCPVCGGAELVHDTRDMPFTYKGQTTQITAVTADWCDACGESLTGPAESERVMRAMNEFRQQVNAQDGNQELIRSVRKQ
LRLSQREAAELFGGGPNAFSRYERGSTEAPQPLVQLFKILGRHPELINELRAG

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1H2LFQ3

References