Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 1038751..1038972 Replicon chromosome
Accession NZ_CP121294
Organism Escherichia coli O155:H21 strain NWU_1

Toxin (Protein)


Gene name ldrD Uniprot ID E0IV43
Locus tag P9N54_RS05180 Protein ID WP_000170926.1
Coordinates 1038751..1038858 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 1038911..1038972 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9N54_RS05150 (1034060) 1034060..1035142 + 1083 WP_000804726.1 peptide chain release factor 1 -
P9N54_RS05155 (1035142) 1035142..1035975 + 834 WP_000456467.1 peptide chain release factor N(5)-glutamine methyltransferase -
P9N54_RS05160 (1035972) 1035972..1036364 + 393 WP_000200392.1 invasion regulator SirB2 -
P9N54_RS05165 (1036368) 1036368..1037177 + 810 WP_001257044.1 invasion regulator SirB1 -
P9N54_RS05170 (1037213) 1037213..1038067 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
P9N54_RS05175 (1038216) 1038216..1038323 - 108 WP_000170954.1 type I toxin-antitoxin system toxin Ldr family protein -
- (1038373) 1038373..1038436 + 64 NuclAT_17 - -
- (1038373) 1038373..1038436 + 64 NuclAT_17 - -
- (1038373) 1038373..1038436 + 64 NuclAT_17 - -
- (1038373) 1038373..1038436 + 64 NuclAT_17 - -
- (1038373) 1038373..1038436 + 64 NuclAT_20 - -
- (1038373) 1038373..1038436 + 64 NuclAT_20 - -
- (1038373) 1038373..1038436 + 64 NuclAT_20 - -
- (1038373) 1038373..1038436 + 64 NuclAT_20 - -
- (1038373) 1038373..1038436 + 64 NuclAT_23 - -
- (1038373) 1038373..1038436 + 64 NuclAT_23 - -
- (1038373) 1038373..1038436 + 64 NuclAT_23 - -
- (1038373) 1038373..1038436 + 64 NuclAT_23 - -
- (1038373) 1038373..1038436 + 64 NuclAT_26 - -
- (1038373) 1038373..1038436 + 64 NuclAT_26 - -
- (1038373) 1038373..1038436 + 64 NuclAT_26 - -
- (1038373) 1038373..1038436 + 64 NuclAT_26 - -
- (1038373) 1038373..1038436 + 64 NuclAT_29 - -
- (1038373) 1038373..1038436 + 64 NuclAT_29 - -
- (1038373) 1038373..1038436 + 64 NuclAT_29 - -
- (1038373) 1038373..1038436 + 64 NuclAT_29 - -
- (1038373) 1038373..1038436 + 64 NuclAT_32 - -
- (1038373) 1038373..1038436 + 64 NuclAT_32 - -
- (1038373) 1038373..1038436 + 64 NuclAT_32 - -
- (1038373) 1038373..1038436 + 64 NuclAT_32 - -
- (1038371) 1038371..1038437 + 67 NuclAT_52 - -
- (1038371) 1038371..1038437 + 67 NuclAT_52 - -
- (1038371) 1038371..1038437 + 67 NuclAT_52 - -
- (1038371) 1038371..1038437 + 67 NuclAT_52 - -
- (1038373) 1038373..1038438 + 66 NuclAT_35 - -
- (1038373) 1038373..1038438 + 66 NuclAT_35 - -
- (1038373) 1038373..1038438 + 66 NuclAT_35 - -
- (1038373) 1038373..1038438 + 66 NuclAT_35 - -
- (1038373) 1038373..1038438 + 66 NuclAT_38 - -
- (1038373) 1038373..1038438 + 66 NuclAT_38 - -
- (1038373) 1038373..1038438 + 66 NuclAT_38 - -
- (1038373) 1038373..1038438 + 66 NuclAT_38 - -
- (1038373) 1038373..1038438 + 66 NuclAT_41 - -
- (1038373) 1038373..1038438 + 66 NuclAT_41 - -
- (1038373) 1038373..1038438 + 66 NuclAT_41 - -
- (1038373) 1038373..1038438 + 66 NuclAT_41 - -
- (1038373) 1038373..1038438 + 66 NuclAT_44 - -
- (1038373) 1038373..1038438 + 66 NuclAT_44 - -
- (1038373) 1038373..1038438 + 66 NuclAT_44 - -
- (1038373) 1038373..1038438 + 66 NuclAT_44 - -
- (1038373) 1038373..1038438 + 66 NuclAT_47 - -
- (1038373) 1038373..1038438 + 66 NuclAT_47 - -
- (1038373) 1038373..1038438 + 66 NuclAT_47 - -
- (1038373) 1038373..1038438 + 66 NuclAT_47 - -
- (1038373) 1038373..1038438 + 66 NuclAT_50 - -
- (1038373) 1038373..1038438 + 66 NuclAT_50 - -
- (1038373) 1038373..1038438 + 66 NuclAT_50 - -
- (1038373) 1038373..1038438 + 66 NuclAT_50 - -
P9N54_RS05180 (1038751) 1038751..1038858 - 108 WP_000170926.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- (1038911) 1038911..1038972 + 62 NuclAT_18 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_18 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_18 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_18 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_21 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_21 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_21 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_21 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_24 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_24 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_24 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_24 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_27 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_27 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_27 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_27 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_30 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_30 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_30 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_30 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_33 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_33 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_33 - Antitoxin
- (1038911) 1038911..1038972 + 62 NuclAT_33 - Antitoxin
- (1038911) 1038911..1038973 + 63 NuclAT_53 - -
- (1038911) 1038911..1038973 + 63 NuclAT_53 - -
- (1038911) 1038911..1038973 + 63 NuclAT_53 - -
- (1038911) 1038911..1038973 + 63 NuclAT_53 - -
- (1038911) 1038911..1038974 + 64 NuclAT_36 - -
- (1038911) 1038911..1038974 + 64 NuclAT_36 - -
- (1038911) 1038911..1038974 + 64 NuclAT_36 - -
- (1038911) 1038911..1038974 + 64 NuclAT_36 - -
- (1038911) 1038911..1038974 + 64 NuclAT_39 - -
- (1038911) 1038911..1038974 + 64 NuclAT_39 - -
- (1038911) 1038911..1038974 + 64 NuclAT_39 - -
- (1038911) 1038911..1038974 + 64 NuclAT_39 - -
- (1038911) 1038911..1038974 + 64 NuclAT_42 - -
- (1038911) 1038911..1038974 + 64 NuclAT_42 - -
- (1038911) 1038911..1038974 + 64 NuclAT_42 - -
- (1038911) 1038911..1038974 + 64 NuclAT_42 - -
- (1038911) 1038911..1038974 + 64 NuclAT_45 - -
- (1038911) 1038911..1038974 + 64 NuclAT_45 - -
- (1038911) 1038911..1038974 + 64 NuclAT_45 - -
- (1038911) 1038911..1038974 + 64 NuclAT_45 - -
- (1038911) 1038911..1038974 + 64 NuclAT_48 - -
- (1038911) 1038911..1038974 + 64 NuclAT_48 - -
- (1038911) 1038911..1038974 + 64 NuclAT_48 - -
- (1038911) 1038911..1038974 + 64 NuclAT_48 - -
- (1038911) 1038911..1038974 + 64 NuclAT_51 - -
- (1038911) 1038911..1038974 + 64 NuclAT_51 - -
- (1038911) 1038911..1038974 + 64 NuclAT_51 - -
- (1038911) 1038911..1038974 + 64 NuclAT_51 - -
P9N54_RS05185 (1039287) 1039287..1039394 - 108 WP_000170965.1 type I toxin-antitoxin system toxin Ldr family protein -
- (1039442) 1039442..1039507 + 66 NuclAT_16 - -
- (1039442) 1039442..1039507 + 66 NuclAT_16 - -
- (1039442) 1039442..1039507 + 66 NuclAT_16 - -
- (1039442) 1039442..1039507 + 66 NuclAT_16 - -
- (1039442) 1039442..1039507 + 66 NuclAT_19 - -
- (1039442) 1039442..1039507 + 66 NuclAT_19 - -
- (1039442) 1039442..1039507 + 66 NuclAT_19 - -
- (1039442) 1039442..1039507 + 66 NuclAT_19 - -
- (1039442) 1039442..1039507 + 66 NuclAT_22 - -
- (1039442) 1039442..1039507 + 66 NuclAT_22 - -
- (1039442) 1039442..1039507 + 66 NuclAT_22 - -
- (1039442) 1039442..1039507 + 66 NuclAT_22 - -
- (1039442) 1039442..1039507 + 66 NuclAT_25 - -
- (1039442) 1039442..1039507 + 66 NuclAT_25 - -
- (1039442) 1039442..1039507 + 66 NuclAT_25 - -
- (1039442) 1039442..1039507 + 66 NuclAT_25 - -
- (1039442) 1039442..1039507 + 66 NuclAT_28 - -
- (1039442) 1039442..1039507 + 66 NuclAT_28 - -
- (1039442) 1039442..1039507 + 66 NuclAT_28 - -
- (1039442) 1039442..1039507 + 66 NuclAT_28 - -
- (1039442) 1039442..1039507 + 66 NuclAT_31 - -
- (1039442) 1039442..1039507 + 66 NuclAT_31 - -
- (1039442) 1039442..1039507 + 66 NuclAT_31 - -
- (1039442) 1039442..1039507 + 66 NuclAT_31 - -
- (1039443) 1039443..1039508 + 66 NuclAT_54 - -
- (1039443) 1039443..1039508 + 66 NuclAT_54 - -
- (1039443) 1039443..1039508 + 66 NuclAT_54 - -
- (1039443) 1039443..1039508 + 66 NuclAT_54 - -
- (1039442) 1039442..1039509 + 68 NuclAT_34 - -
- (1039442) 1039442..1039509 + 68 NuclAT_34 - -
- (1039442) 1039442..1039509 + 68 NuclAT_34 - -
- (1039442) 1039442..1039509 + 68 NuclAT_34 - -
- (1039442) 1039442..1039509 + 68 NuclAT_37 - -
- (1039442) 1039442..1039509 + 68 NuclAT_37 - -
- (1039442) 1039442..1039509 + 68 NuclAT_37 - -
- (1039442) 1039442..1039509 + 68 NuclAT_37 - -
- (1039442) 1039442..1039509 + 68 NuclAT_40 - -
- (1039442) 1039442..1039509 + 68 NuclAT_40 - -
- (1039442) 1039442..1039509 + 68 NuclAT_40 - -
- (1039442) 1039442..1039509 + 68 NuclAT_40 - -
- (1039442) 1039442..1039509 + 68 NuclAT_43 - -
- (1039442) 1039442..1039509 + 68 NuclAT_43 - -
- (1039442) 1039442..1039509 + 68 NuclAT_43 - -
- (1039442) 1039442..1039509 + 68 NuclAT_43 - -
- (1039442) 1039442..1039509 + 68 NuclAT_46 - -
- (1039442) 1039442..1039509 + 68 NuclAT_46 - -
- (1039442) 1039442..1039509 + 68 NuclAT_46 - -
- (1039442) 1039442..1039509 + 68 NuclAT_46 - -
- (1039442) 1039442..1039509 + 68 NuclAT_49 - -
- (1039442) 1039442..1039509 + 68 NuclAT_49 - -
- (1039442) 1039442..1039509 + 68 NuclAT_49 - -
- (1039442) 1039442..1039509 + 68 NuclAT_49 - -
P9N54_RS05190 (1039799) 1039799..1040899 - 1101 WP_001295620.1 sodium-potassium/proton antiporter ChaA -
P9N54_RS05195 (1041169) 1041169..1041399 + 231 WP_001146442.1 putative cation transport regulator ChaB -
P9N54_RS05200 (1041557) 1041557..1042252 + 696 WP_001297117.1 glutathione-specific gamma-glutamylcyclotransferase -
P9N54_RS05205 (1042296) 1042296..1042649 - 354 WP_001169669.1 DsrE/F sulfur relay family protein YchN -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3983.84 Da        Isoelectric Point: 11.6501

>T276184 WP_000170926.1 NZ_CP121294:c1038858-1038751 [Escherichia coli O155:H21]
MTLAKFAMIFWHDLAAPILAGIITAAIVGWWRNRK

Download         Length: 108 bp

Antitoxin


Download         Length: 62 bp

>AT276184 NZ_CP121294:1038911-1038972 [Escherichia coli O155:H21]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0E0Y1K9

Antitoxin

Download structure file

References