276078

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2622040..2622224 Replicon chromosome
Accession NZ_CP121204
Organism Staphylococcus aureus strain SA0907

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag P7F77_RS13280 Protein ID WP_000482647.1
Coordinates 2622117..2622224 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2622040..2622100 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P7F77_RS13265 2617550..2617717 - 168 WP_031875065.1 hypothetical protein -
P7F77_RS13270 2617948..2619681 - 1734 WP_000488491.1 ABC transporter ATP-binding protein -
P7F77_RS13275 2619730..2621469 - 1740 WP_001064832.1 ABC transporter ATP-binding protein -
- 2622040..2622100 + 61 - - Antitoxin
P7F77_RS13280 2622117..2622224 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
P7F77_RS13285 2622358..2622744 - 387 WP_000779354.1 flippase GtxA -
P7F77_RS13290 2623012..2624154 + 1143 WP_031875064.1 glycerate kinase -
P7F77_RS13295 2624214..2624873 + 660 WP_000831298.1 membrane protein -
P7F77_RS13300 2625053..2626264 + 1212 WP_001191975.1 multidrug effflux MFS transporter -
P7F77_RS13305 2626387..2626860 - 474 WP_000456490.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T276078 WP_000482647.1 NZ_CP121204:c2622224-2622117 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT276078 NZ_CP121204:2622040-2622100 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References