Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 575101..575939 Replicon plasmid unnamed
Accession NZ_CP121109
Organism Pantoea sp. X85

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag P6287_RS22245 Protein ID WP_277975061.1
Coordinates 575101..575583 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag P6287_RS22250 Protein ID WP_277975062.1
Coordinates 575601..575939 (-) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6287_RS22225 (P6287_22225) 570388..571350 + 963 WP_277975348.1 ABC transporter substrate-binding protein -
P6287_RS22230 (P6287_22230) 571358..572773 + 1416 WP_277975058.1 amidohydrolase family protein -
P6287_RS22235 (P6287_22235) 572779..574299 - 1521 WP_277975059.1 MDR family MFS transporter -
P6287_RS22240 (P6287_22240) 574379..575044 + 666 WP_277975060.1 TetR/AcrR family transcriptional regulator -
P6287_RS22245 (P6287_22245) 575101..575583 - 483 WP_277975061.1 type II toxin-antitoxin system YhaV family toxin Toxin
P6287_RS22250 (P6287_22250) 575601..575939 - 339 WP_277975062.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
P6287_RS22255 (P6287_22255) 576155..576721 + 567 WP_277975063.1 peroxiredoxin -
P6287_RS22260 (P6287_22260) 576737..577966 + 1230 WP_192413167.1 thioredoxin family protein -
P6287_RS22265 (P6287_22265) 577984..578541 + 558 WP_192413169.1 sigma-70 family RNA polymerase sigma factor -
P6287_RS22270 (P6287_22270) 578528..579157 + 630 WP_277975064.1 NrsF family protein -
P6287_RS22275 (P6287_22275) 579320..579589 + 270 WP_101761698.1 DUF1471 family periplasmic protein YahO -
P6287_RS22280 (P6287_22280) 579757..580824 - 1068 WP_277975065.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..771939 771939


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(14-112)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 18802.44 Da        Isoelectric Point: 9.2890

>T275696 WP_277975061.1 NZ_CP121109:c575583-575101 [Pantoea sp. X85]
VDYMEINGWKFYFHACFSAQVTSLAQEVLQLRVEKPHEYHKKKQTKLLAAIYKVVTEVIARDPLNPQFRQGGTLGDENRY
WFRAKFLQQFRLFFRCSEQSKTIILGWVNDFGTLRAYESKTDAYKTFKRMLDAGHPPSDWEQLLRESTGESGFLFQAPFS

Download         Length: 483 bp

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12471.05 Da        Isoelectric Point: 4.1760

>AT275696 WP_277975062.1 NZ_CP121109:c575939-575601 [Pantoea sp. X85]
VFKFDLVDVSLRAESRLTERSQTTIPAAIRDALQLKPGEIIEYSLLSGGKVIMSKQNDEQDDPAVQHFLTFLERDMVSNP
QHIHSVPVELWSGLENLVAGIDVDLDAPLTDD

Download         Length: 339 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References