Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 18464..19115 Replicon plasmid unnamed
Accession NZ_CP121109
Organism Pantoea sp. X85

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag P6287_RS19800 Protein ID WP_137387145.1
Coordinates 18464..18808 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag P6287_RS19805 Protein ID WP_210080109.1
Coordinates 18801..19115 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6287_RS19785 (P6287_19785) 14099..15538 + 1440 WP_271460188.1 MFS transporter -
P6287_RS19790 (P6287_19790) 15535..16749 + 1215 WP_277975160.1 acyl-CoA dehydrogenase family protein -
P6287_RS19800 (P6287_19800) 18464..18808 + 345 WP_137387145.1 toxin Toxin
P6287_RS19805 (P6287_19805) 18801..19115 + 315 WP_210080109.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
P6287_RS19810 (P6287_19810) 19250..20197 - 948 WP_277975162.1 sulfonate ABC transporter substrate-binding protein -
P6287_RS19815 (P6287_19815) 20452..22509 + 2058 WP_277975163.1 FUSC family protein -
P6287_RS19820 (P6287_19820) 22525..23214 + 690 WP_192414671.1 aspartate/glutamate racemase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..771939 771939


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-88)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13492.32 Da        Isoelectric Point: 9.9070

>T275694 WP_137387145.1 NZ_CP121109:18464-18808 [Pantoea sp. X85]
MHATFIELSSFQKYRVEYLSDDQFRLFQNMLMADPEKGDVIPDTGGLRKVRFRDERRNKGTRGGIRVIYYWTNEKGQFIL
FTIYDKDQRDDLTKQQRDALGSALNVIKKGLRHD

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12024.81 Da        Isoelectric Point: 9.8806

>AT275694 WP_210080109.1 NZ_CP121109:18801-19115 [Pantoea sp. X85]
MTERDIFSELMTGMQELKDHKDGKITLKTYKVSKRAPVTIAPQELRDVREKLNLSQAVFAHYLHTGETTYQNWEQGRSRP
NAQAVLLIRMVQQNPETLKTLAQL

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References