Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 484353..484938 Replicon chromosome
Accession NZ_CP121108
Organism Pantoea sp. X85

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag P6287_RS02150 Protein ID WP_277974900.1
Coordinates 484353..484652 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag P6287_RS02155 Protein ID WP_008109607.1
Coordinates 484639..484938 (+) Length 100 a.a.

Genomic Context

P6287_RS02140P6287_RS02150P6287_RS02155P6287_RS02130P6287_RS02135P6287_RS02145P6287_RS02165P6287_RS02170P6287_RS02175
Location: 482075..482995 (921 bp)
Type: Others
Protein ID: WP_277974435.1
Location: 484353..484652 (300 bp)
Type: Toxin
Protein ID: WP_277974900.1
Location: 484639..484938 (300 bp)
Type: Antitoxin
Protein ID: WP_008109607.1
Location: 480252..480962 (711 bp)
Type: Others
Protein ID: WP_137385029.1
Location: 480965..481804 (840 bp)
Type: Others
Protein ID: WP_277974434.1
Location: 483130..483825 (696 bp)
Type: Others
Protein ID: WP_101762304.1
Location: 485211..485789 (579 bp)
Type: Others
Protein ID: WP_101762303.1
Location: 485856..487556 (1701 bp)
Type: Others
Protein ID: WP_277974436.1
Location: 487640..488941 (1302 bp)
Type: Others
Protein ID: WP_101762301.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
P6287_RS02130 (P6287_02130)480252..480962-711WP_137385029.15-oxoprolinase subunit PxpB-
P6287_RS02135 (P6287_02135)480965..481804-840WP_277974434.1transporter substrate-binding domain-containing protein-
P6287_RS02140 (P6287_02140)482075..482995+921WP_277974435.1DMT family transporter-
P6287_RS02145 (P6287_02145)483130..483825-696WP_101762304.1RraA family protein-
P6287_RS02150 (P6287_02150)484353..484652+300WP_277974900.1type II toxin-antitoxin system RelE/ParE family toxinToxin
P6287_RS02155 (P6287_02155)484639..484938+300WP_008109607.1helix-turn-helix transcriptional regulatorAntitoxin
P6287_RS02165 (P6287_02165)485211..485789-579WP_101762303.1transcriptional regulator-
P6287_RS02170 (P6287_02170)485856..487556-1701WP_277974436.1protein-disulfide reductase DsbD-
P6287_RS02175 (P6287_02175)487640..488941-1302WP_101762301.1anaerobic C4-dicarboxylate transporter-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(4-88)

Antitoxin

Cro/C1-type helix-turn-helix domain

(31-80)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11229.07 Da        Isoelectric Point: 9.9714

>T275688 WP_277974900.1 NZ_CP121108:484353-484652 [Pantoea sp. X85]
MVEDVLSSLELLKVFGPMLGRPDVDTVTGSRFANMKELRVQSNGRPIRAFFAFDPVRKAIVLCAGDKTGVNQKRFYQSMI
KLADKEYKQHLEELTHAKT

Download         Length: 300 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11155.97 Da        Isoelectric Point: 6.4051

>AT275688 WP_008109607.1 NZ_CP121108:484639-484938 [Pantoea sp. X85]
MPKLEELIAQRSPESQERIKNKADQKIMEIRLRQLREELELSQVQLAEKMGISQPAIAAIEARGDEIKLSSLKKYVEALG
GKLSLNVELPTGDGRIFQI

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References