Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 484353..484938 Replicon chromosome
Accession NZ_CP121108
Organism Pantoea sp. X85

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag P6287_RS02150 Protein ID WP_277974900.1
Coordinates 484353..484652 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag P6287_RS02155 Protein ID WP_008109607.1
Coordinates 484639..484938 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6287_RS02130 (P6287_02130) 480252..480962 - 711 WP_137385029.1 5-oxoprolinase subunit PxpB -
P6287_RS02135 (P6287_02135) 480965..481804 - 840 WP_277974434.1 transporter substrate-binding domain-containing protein -
P6287_RS02140 (P6287_02140) 482075..482995 + 921 WP_277974435.1 DMT family transporter -
P6287_RS02145 (P6287_02145) 483130..483825 - 696 WP_101762304.1 RraA family protein -
P6287_RS02150 (P6287_02150) 484353..484652 + 300 WP_277974900.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P6287_RS02155 (P6287_02155) 484639..484938 + 300 WP_008109607.1 helix-turn-helix transcriptional regulator Antitoxin
P6287_RS02165 (P6287_02165) 485211..485789 - 579 WP_101762303.1 transcriptional regulator -
P6287_RS02170 (P6287_02170) 485856..487556 - 1701 WP_277974436.1 protein-disulfide reductase DsbD -
P6287_RS02175 (P6287_02175) 487640..488941 - 1302 WP_101762301.1 anaerobic C4-dicarboxylate transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(4-88)

Antitoxin

Cro/C1-type helix-turn-helix domain

(31-80)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11229.07 Da        Isoelectric Point: 9.9714

>T275688 WP_277974900.1 NZ_CP121108:484353-484652 [Pantoea sp. X85]
MVEDVLSSLELLKVFGPMLGRPDVDTVTGSRFANMKELRVQSNGRPIRAFFAFDPVRKAIVLCAGDKTGVNQKRFYQSMI
KLADKEYKQHLEELTHAKT

Download         Length: 300 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11155.97 Da        Isoelectric Point: 6.4051

>AT275688 WP_008109607.1 NZ_CP121108:484639-484938 [Pantoea sp. X85]
MPKLEELIAQRSPESQERIKNKADQKIMEIRLRQLREELELSQVQLAEKMGISQPAIAAIEARGDEIKLSSLKKYVEALG
GKLSLNVELPTGDGRIFQI

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References