Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2670270..2670772 Replicon chromosome
Accession NZ_CP120978
Organism Moellerella wisconsensis strain XJ22MSE3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag P8A17_RS11840 Protein ID WP_241500949.1
Coordinates 2670518..2670772 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag P8A17_RS11835 Protein ID WP_241500948.1
Coordinates 2670270..2670521 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8A17_RS11800 2665531..2666595 + 1065 WP_277850155.1 T6SS immunity protein Tli4 family protein -
P8A17_RS11805 2666652..2666747 + 96 WP_241500938.1 T6SS immunity protein Tli4 family protein -
P8A17_RS11810 2666789..2667079 + 291 WP_241500939.1 hypothetical protein -
P8A17_RS11815 2667076..2667225 + 150 Protein_2290 DUF6392 family protein -
P8A17_RS11820 2667419..2667757 + 339 WP_241540503.1 hypothetical protein -
P8A17_RS11825 2668381..2669010 + 630 WP_241500946.1 DNA-binding protein -
P8A17_RS11830 2669034..2669681 - 648 WP_241500947.1 RES domain-containing protein -
P8A17_RS11835 2670270..2670521 + 252 WP_241500948.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
P8A17_RS11840 2670518..2670772 + 255 WP_241500949.1 Txe/YoeB family addiction module toxin Toxin
P8A17_RS11845 2670820..2671164 - 345 WP_241500950.1 hypothetical protein -
P8A17_RS11850 2671688..2672134 + 447 WP_241500951.1 DUF3290 domain-containing protein -
P8A17_RS11855 2672143..2672793 + 651 WP_053907799.1 DUF421 domain-containing protein -
P8A17_RS11860 2673288..2674235 + 948 WP_241543284.1 Rpn family recombination-promoting nuclease/putative transposase -
P8A17_RS11865 2674254..2674481 + 228 WP_277850156.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9926.30 Da        Isoelectric Point: 9.7120

>T275506 WP_241500949.1 NZ_CP120978:2670518-2670772 [Moellerella wisconsensis]
VKLTWSAEAWEDYLYWQETDRKTVKKINELIKNASRTPFEGKGKPEPLKHNLAGFWSRRITAEHRLVYAVSNDSLLIASC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9500.89 Da        Isoelectric Point: 5.1367

>AT275506 WP_241500948.1 NZ_CP120978:2670270-2670521 [Moellerella wisconsensis]
MKAVSYSEARQNLSTTMIQTVEDRVPVLITRQNGESCVLMSLDEYNSLEETAYLMRSPKNARRLMDSIESLKDGKGMERE
IIK

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References