275499

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2670985..2671487 Replicon chromosome
Accession NZ_CP120974
Organism Moellerella wisconsensis strain XJ22MSE2

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag P8A16_RS11845 Protein ID WP_241500949.1
Coordinates 2671233..2671487 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag P8A16_RS11840 Protein ID WP_241500948.1
Coordinates 2670985..2671236 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8A16_RS11805 2666246..2667310 + 1065 WP_277850155.1 T6SS immunity protein Tli4 family protein -
P8A16_RS11810 2667367..2667462 + 96 WP_241500938.1 T6SS immunity protein Tli4 family protein -
P8A16_RS11815 2667504..2667794 + 291 WP_241500939.1 hypothetical protein -
P8A16_RS11820 2667791..2667940 + 150 Protein_2291 DUF6392 family protein -
P8A16_RS11825 2668134..2668472 + 339 WP_241540503.1 hypothetical protein -
P8A16_RS11830 2669096..2669725 + 630 WP_241500946.1 DNA-binding protein -
P8A16_RS11835 2669749..2670396 - 648 WP_241500947.1 RES domain-containing protein -
P8A16_RS11840 2670985..2671236 + 252 WP_241500948.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
P8A16_RS11845 2671233..2671487 + 255 WP_241500949.1 Txe/YoeB family addiction module toxin Toxin
P8A16_RS11850 2671535..2671879 - 345 WP_241500950.1 hypothetical protein -
P8A16_RS11855 2672403..2672849 + 447 WP_241500951.1 DUF3290 domain-containing protein -
P8A16_RS11860 2672858..2673508 + 651 WP_053907799.1 DUF421 domain-containing protein -
P8A16_RS11865 2674003..2674950 + 948 WP_241543284.1 Rpn family recombination-promoting nuclease/putative transposase -
P8A16_RS11870 2674969..2675196 + 228 WP_277850156.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9926.30 Da        Isoelectric Point: 9.7120

>T275499 WP_241500949.1 NZ_CP120974:2671233-2671487 [Moellerella wisconsensis]
VKLTWSAEAWEDYLYWQETDRKTVKKINELIKNASRTPFEGKGKPEPLKHNLAGFWSRRITAEHRLVYAVSNDSLLIASC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9500.89 Da        Isoelectric Point: 5.1367

>AT275499 WP_241500948.1 NZ_CP120974:2670985-2671236 [Moellerella wisconsensis]
MKAVSYSEARQNLSTTMIQTVEDRVPVLITRQNGESCVLMSLDEYNSLEETAYLMRSPKNARRLMDSIESLKDGKGMERE
IIK

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References