Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2024951..2025651 Replicon chromosome
Accession NZ_CP120969
Organism Pseudomonas putida strain AHSWHJXPP1

Toxin (Protein)


Gene name mqsR Uniprot ID A0A2I0CDW7
Locus tag P3X84_RS09510 Protein ID WP_003254238.1
Coordinates 2024951..2025247 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID I7AUJ7
Locus tag P3X84_RS09515 Protein ID WP_003254235.1
Coordinates 2025250..2025651 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P3X84_RS09490 (P3X84_09490) 2020587..2022212 + 1626 WP_060538696.1 twin-arginine translocation signal domain-containing protein -
P3X84_RS09495 (P3X84_09495) 2022334..2022810 + 477 WP_003254241.1 sigma-70 family RNA polymerase sigma factor -
P3X84_RS09500 (P3X84_09500) 2022979..2023458 + 480 WP_012051716.1 hypothetical protein -
P3X84_RS09505 (P3X84_09505) 2023531..2024856 + 1326 WP_047604115.1 MFS transporter -
P3X84_RS09510 (P3X84_09510) 2024951..2025247 + 297 WP_003254238.1 type II toxin-antitoxin system MqsR family toxin Toxin
P3X84_RS09515 (P3X84_09515) 2025250..2025651 + 402 WP_003254235.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
P3X84_RS09520 (P3X84_09520) 2025723..2027405 - 1683 WP_010954959.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
P3X84_RS09525 (P3X84_09525) 2027941..2028690 + 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
P3X84_RS09530 (P3X84_09530) 2028691..2029620 + 930 WP_003254230.1 FAD-binding protein -
P3X84_RS09535 (P3X84_09535) 2029696..2030517 + 822 WP_003254229.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11110.18 Da        Isoelectric Point: 10.2270

>T275488 WP_003254238.1 NZ_CP120969:2024951-2025247 [Pseudomonas putida]
MEKRMPNCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14684.76 Da        Isoelectric Point: 4.9531

>AT275488 WP_003254235.1 NZ_CP120969:2025250-2025651 [Pseudomonas putida]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I0CDW7

Antitoxin

Source ID Structure
AlphaFold DB I7AUJ7

References