Detailed information of TA system TA275350

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 1434610..1434856
• Replicon: chromosome
• Accession: NZ_CP120681
• Organism: Bacillus subtilis strain DSM 10

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: P5655_RS07510
• Protein ID: WP_109789044.1
• Coordinates: 1434610..1434702 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	1434683..1434856 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P5655_RS07495	1429770..1430105	+	336	WP_009967409.1	hypothetical protein	-
P5655_RS07500	1430152..1433736	-	3585	WP_277723653.1	P-loop NTPase fold protein	-
P5655_RS07505	1433989..1434321	-	333	WP_026009814.1	hypothetical protein	-
P5655_RS07510	1434610..1434702	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	1434683..1434856	-	174	-	-	Antitoxin
P5655_RS07515	1434971..1435813	-	843	WP_003231327.1	hypothetical protein	-
P5655_RS07520	1436013..1436471	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
P5655_RS07525	1436481..1438283	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
P5655_RS07530	1438385..1438942	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1421006..1444273	23267

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T275350 WP_109789044.1 NZ_CP120681:1434610-1434702 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

Antitoxin

Nucleotide

• Length: 174 bp

>AT275350 NZ_CP120681:c1434856-1434683 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin