Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 401907..402494 Replicon chromosome
Accession NZ_CP120638
Organism Rhizobium sp. 32-5/1

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag P6U16_RS02040 Protein ID WP_277702432.1
Coordinates 402213..402494 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag P6U16_RS02035 Protein ID WP_277702431.1
Coordinates 401907..402203 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6U16_RS02005 (P6U16_02005) 397629..398654 - 1026 WP_277702425.1 tRNA dihydrouridine synthase DusB -
P6U16_RS02010 (P6U16_02010) 398839..400050 + 1212 WP_277702426.1 bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase -
P6U16_RS02015 (P6U16_02015) 400047..400550 + 504 WP_277702427.1 CinA family protein -
P6U16_RS02020 (P6U16_02020) 400551..401156 - 606 WP_277702428.1 hypothetical protein -
P6U16_RS02025 (P6U16_02025) 401129..401383 - 255 WP_277702429.1 hypothetical protein -
P6U16_RS02030 (P6U16_02030) 401448..401900 - 453 WP_277702430.1 type II toxin-antitoxin system RatA family toxin -
P6U16_RS02035 (P6U16_02035) 401907..402203 - 297 WP_277702431.1 HigA family addiction module antitoxin Antitoxin
P6U16_RS02040 (P6U16_02040) 402213..402494 - 282 WP_277702432.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P6U16_RS02045 (P6U16_02045) 402531..403508 - 978 WP_277702433.1 lipoyl synthase -
P6U16_RS02050 (P6U16_02050) 403592..405036 - 1445 Protein_399 dihydrolipoyl dehydrogenase -
P6U16_RS02055 (P6U16_02055) 405029..405637 - 609 WP_277702434.1 GNAT family N-acetyltransferase -
P6U16_RS02060 (P6U16_02060) 405639..406280 - 642 WP_277702435.1 SGNH/GDSL hydrolase family protein -
P6U16_RS02065 (P6U16_02065) 406285..406800 - 516 WP_277702436.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-69)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10867.44 Da        Isoelectric Point: 10.0216

>T275314 WP_277702432.1 NZ_CP120638:c402494-402213 [Rhizobium sp. 32-5/1]
MIKGFRNKETEILFRSNGRSRFPPDIVPRARRKLLVLDAAFKLADVTVPPSNRLELLSGNRQGQHSIRINDQWRICFVWD
NGHAHEVEICDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11019.64 Da        Isoelectric Point: 5.8393

>AT275314 WP_277702431.1 NZ_CP120638:c402203-401907 [Rhizobium sp. 32-5/1]
MQFVMENPIHPGEILKEEFLKEYALTAYRVAESIGVPRTRLERILRGENGITADTALRLARYFGNSPEFWLNLQRTYDLA
LAAKNAGDLNAIVPVQAA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References