Detailed information of TA system TA275239

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2669640..2669886
• Replicon: chromosome
• Accession: NZ_CP120598
• Organism: Bacillus subtilis strain PRO115

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: P5622_RS14300
• Protein ID: WP_109789044.1
• Coordinates: 2669794..2669886 (-)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2669640..2669813 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P5622_RS14280	2665554..2666111	+	558	WP_004399321.1	SMI1/KNR4 family protein	-
P5622_RS14285	2666213..2668015	+	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
P5622_RS14290	2668025..2668483	+	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
P5622_RS14295	2668683..2669525	+	843	WP_003231327.1	hypothetical protein	-
-	2669640..2669813	+	174	-	-	Antitoxin
P5622_RS14300	2669794..2669886	-	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
P5622_RS14305	2670175..2670506	+	332	Protein_2764	hypothetical protein	-
P5622_RS14310	2670739..2674344	+	3606	WP_004399367.1	P-loop NTPase fold protein	-
P5622_RS14315	2674391..2674726	-	336	WP_009967409.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2665548..2683900	18352

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T275239 WP_109789044.1 NZ_CP120598:c2669886-2669794 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

Antitoxin

Nucleotide

• Length: 174 bp

>AT275239 NZ_CP120598:2669640-2669813 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin