Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4177922..4178180 Replicon chromosome
Accession NZ_CP120549
Organism Escherichia coli strain B1172

Toxin (Protein)


Gene name hokC Uniprot ID -
Locus tag P5710_RS20265 Protein ID WP_001519334.1
Coordinates 4178028..4178180 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4177922..4177979 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5710_RS20250 4173751..4175010 - 1260 WP_000494929.1 hypothetical protein -
P5710_RS20255 4175139..4176632 - 1494 WP_001350365.1 sulfatase-like hydrolase/transferase -
P5710_RS20260 4176652..4177413 - 762 WP_001274832.1 outer membrane protein OmpK -
- 4177922..4177979 - 58 - - Antitoxin
P5710_RS20265 4178028..4178180 + 153 WP_001519334.1 type I toxin-antitoxin system toxin MokC Toxin
P5710_RS20270 4178285..4179415 - 1131 WP_001118464.1 molecular chaperone DnaJ -
P5710_RS20275 4179504..4181420 - 1917 WP_000516135.1 molecular chaperone DnaK -
P5710_RS20280 4181792..4182196 + 405 WP_000843692.1 DUF2541 family protein -
P5710_RS20285 4182222..4182935 + 714 WP_001102393.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5515.59 Da        Isoelectric Point: 7.1312

>T275111 WP_001519334.1 NZ_CP120549:4178028-4178180 [Escherichia coli]
MKQHKAMIIALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT275111 NZ_CP120549:c4177979-4177922 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References