Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 223904..224168 | Replicon | plasmid p514780 |
Accession | NZ_CP119987 | ||
Organism | Salmonella enterica strain CRIN514780 |
Toxin (Protein)
Gene name | pndA | Uniprot ID | U9Z417 |
Locus tag | P2V97_RS24025 | Protein ID | WP_001387489.1 |
Coordinates | 223904..224056 (-) | Length | 51 a.a. |
Antitoxin (RNA)
Gene name | pndB | ||
Locus tag | - | ||
Coordinates | 224108..224168 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
P2V97_RS23995 (219170) | 219170..221338 | + | 2169 | WP_058649949.1 | DotA/TraY family protein | - |
P2V97_RS24000 (221409) | 221409..222071 | + | 663 | WP_000644796.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
P2V97_RS24005 (222143) | 222143..222352 | - | 210 | WP_000062603.1 | HEAT repeat domain-containing protein | - |
P2V97_RS24010 (222744) | 222744..222920 | + | 177 | WP_001054897.1 | hypothetical protein | - |
P2V97_RS24015 (222985) | 222985..223080 | - | 96 | WP_000609148.1 | DinQ-like type I toxin DqlB | - |
P2V97_RS24020 (223581) | 223581..223832 | + | 252 | WP_001291964.1 | hypothetical protein | - |
P2V97_RS24025 (223904) | 223904..224056 | - | 153 | WP_001387489.1 | Hok/Gef family protein | Toxin |
- (224108) | 224108..224168 | + | 61 | NuclAT_0 | - | Antitoxin |
- (224108) | 224108..224168 | + | 61 | NuclAT_0 | - | Antitoxin |
- (224108) | 224108..224168 | + | 61 | NuclAT_0 | - | Antitoxin |
- (224108) | 224108..224168 | + | 61 | NuclAT_0 | - | Antitoxin |
P2V97_RS24030 (224683) | 224683..225462 | + | 780 | WP_275450201.1 | protein FinQ | - |
P2V97_RS24035 (225769) | 225769..226977 | + | 1209 | WP_001383960.1 | IncI1-type conjugal transfer protein TrbA | - |
P2V97_RS24040 (226996) | 226996..228066 | + | 1071 | WP_000151583.1 | IncI1-type conjugal transfer protein TrbB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Conjugative plasmid | ant(3'')-Ia / qacE / sul1 / tet(A) / blaCTX-M-65 / floR / aph(4)-Ia / aac(3)-IVa / aph(3')-Ia | faeC / faeD / faeD / faeE / faeF / faeH / faeI / fyuA / ybtE / ybtT / ybtU / irp1 / irp2 / ybtA / ybtP / ybtQ / ybtX / ybtS | 1..312164 | 312164 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5761.10 Da Isoelectric Point: 8.7948
>T274582 WP_001387489.1 NZ_CP119987:c224056-223904 [Salmonella enterica]
MPQRTFLMMLIVVCVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
MPQRTFLMMLIVVCVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
Download Length: 153 bp
Antitoxin
Download Length: 61 bp
>AT274582 NZ_CP119987:224108-224168 [Salmonella enterica]
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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