Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 1981470..1981990 Replicon chromosome
Accession NZ_CP119863
Organism Agrobacterium fabrum strain NT1RE

Toxin (Protein)


Gene name yoeB Uniprot ID A9CID9
Locus tag NT1RE_RS09890 Protein ID WP_010972002.1
Coordinates 1981470..1981739 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID Q7CY23
Locus tag NT1RE_RS09895 Protein ID WP_010972003.1
Coordinates 1981736..1981990 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NT1RE_RS09870 (NT1RE_09870) 1976501..1978195 - 1695 WP_010971998.1 iron ABC transporter permease -
NT1RE_RS09875 (NT1RE_09875) 1978205..1979188 - 984 WP_010971999.1 ABC transporter substrate-binding protein -
NT1RE_RS09880 (NT1RE_09880) 1979497..1980741 - 1245 WP_010972000.1 PLP-dependent aminotransferase family protein -
NT1RE_RS09885 (NT1RE_09885) 1981016..1981465 + 450 WP_010972001.1 RbsD/FucU family protein -
NT1RE_RS09890 (NT1RE_09890) 1981470..1981739 - 270 WP_010972002.1 Txe/YoeB family addiction module toxin Toxin
NT1RE_RS09895 (NT1RE_09895) 1981736..1981990 - 255 WP_010972003.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NT1RE_RS09900 (NT1RE_09900) 1982129..1983148 - 1020 WP_010972004.1 ketol-acid reductoisomerase -
NT1RE_RS09905 (NT1RE_09905) 1983196..1983849 - 654 WP_006311841.1 TetR/AcrR family transcriptional regulator -
NT1RE_RS09910 (NT1RE_09910) 1984249..1985154 - 906 WP_010972005.1 AraC family transcriptional regulator -
NT1RE_RS09915 (NT1RE_09915) 1985344..1986390 + 1047 WP_006311839.1 NAD(P)-dependent alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10612.09 Da        Isoelectric Point: 9.8742

>T274475 WP_010972002.1 NZ_CP119863:c1981739-1981470 [Agrobacterium fabrum]
MKLVWTLSSWDDYEFWQRTDARMVEKINDLIRNAKRTPFAGLGKPEPLKGDMAGYWSRRITAEHRFVYRVSGSGSEQRLE
VIQCRFHYQ

Download         Length: 270 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9577.70 Da        Isoelectric Point: 4.6749

>AT274475 WP_010972003.1 NZ_CP119863:c1981990-1981736 [Agrobacterium fabrum]
MANVRFTEFRQNFATHFDRVLETRAPLLVTRQGKEAVVVLAEGEYESMQETLHLLSNPANASRLRASMGELERGDTIERD
PTEE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 6N90

Antitoxin

Source ID Structure
AlphaFold DB Q7CY23

References