Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1476215..1476789 Replicon chromosome
Accession NZ_CP119772
Organism Pseudomonas sp. D3

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag P3S72_RS06500 Protein ID WP_276197903.1
Coordinates 1476215..1476490 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag P3S72_RS06505 Protein ID WP_276196684.1
Coordinates 1476499..1476789 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P3S72_RS06480 (P3S72_06480) 1471387..1471761 + 375 WP_276196680.1 GtrA family protein -
P3S72_RS06485 (P3S72_06485) 1471758..1472702 + 945 WP_276196681.1 glycosyltransferase family 2 protein -
P3S72_RS06490 (P3S72_06490) 1472724..1474259 + 1536 WP_276196682.1 glucosyltransferase domain-containing protein -
P3S72_RS06495 (P3S72_06495) 1474290..1475909 - 1620 WP_276196683.1 FMN-binding glutamate synthase family protein -
P3S72_RS06500 (P3S72_06500) 1476215..1476490 + 276 WP_276197903.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P3S72_RS06505 (P3S72_06505) 1476499..1476789 + 291 WP_276196684.1 HigA family addiction module antitoxin Antitoxin
P3S72_RS06510 (P3S72_06510) 1476870..1478258 - 1389 WP_276196685.1 ATP-binding protein -
P3S72_RS06515 (P3S72_06515) 1478255..1480069 - 1815 WP_247403209.1 ATP-binding protein -
P3S72_RS06520 (P3S72_06520) 1480080..1481066 - 987 WP_247403210.1 cytochrome c peroxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(3-91)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(6-78)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10421.83 Da        Isoelectric Point: 7.2443

>T274444 WP_276197903.1 NZ_CP119772:1476215-1476490 [Pseudomonas sp. D3]
IRSFKCAETQNLFETGRIRRWSAVVSVVERKLSMLDAAVDLADLRSPPGNRLEPLYGDREGQHSIRINGQFRVCFIWGPH
GPENVEIVDYH

Download         Length: 276 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10555.30 Da        Isoelectric Point: 6.4517

>AT274444 WP_276196684.1 NZ_CP119772:1476499-1476789 [Pseudomonas sp. D3]
MFKNGMRPVHPGEILKEEYLEPLGLTAAALACAPTVNDIVLMRRSISADVALRLAVALETSAQFWLNLQTAYDLRTAEIA
KGAQIYKEVERVAHCA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References