Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 166064..167294 Replicon chromosome
Accession NZ_CP119766
Organism Flavobacterium sp. CJ75

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag P2W65_RS00840 Protein ID WP_289662830.1
Coordinates 166064..166987 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag P2W65_RS00845 Protein ID WP_289662832.1
Coordinates 166980..167294 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P2W65_RS00825 161875..164493 + 2619 WP_289662825.1 TonB-dependent receptor -
P2W65_RS00830 164498..165337 + 840 WP_289662827.1 DUF4249 domain-containing protein -
P2W65_RS00835 165451..166047 - 597 WP_289662829.1 hypothetical protein -
P2W65_RS00840 166064..166987 - 924 WP_289662830.1 HipA domain-containing protein Toxin
P2W65_RS00845 166980..167294 - 315 WP_289662832.1 HipA N-terminal domain-containing protein Antitoxin
P2W65_RS00850 167298..167507 - 210 WP_289662834.1 helix-turn-helix domain-containing protein -
P2W65_RS00855 167736..169538 - 1803 WP_289662835.1 glycoside hydrolase family 2 TIM barrel-domain containing protein -
P2W65_RS00860 169962..171380 - 1419 WP_289662836.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(52-278)

Antitoxin

HipA, N-terminal subdomain 1

(3-98)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 35480.15 Da        Isoelectric Point: 9.6681

>T274441 WP_289662830.1 NZ_CP119766:c166987-166064 [Flavobacterium sp. CJ75]
MNRCPITYELCGDGLYSSKGLRMLSPKLNSFHNLPFSASEQRQEAVNRASKLSIQGVQPKLSAVLSIKKQQFDIVDQFGN
FIIKPQSDIFPELPENEDLTMRMAKLYGIDVPLHGLVYSKDDSKSYFIKRFDRYSKGRKFATEDFAQLTGSSRDTKYNFT
MEKIVKVLDDFCTFPSIEKAALFKRVLFCFITGNEDMHLKNFSLITKSGKTTLAPAYDFLNSSIAIKKPQEEMALKLKGK
KSNFKAVDLIDYFAKERLGLNDKIIEQIIKKMFDNVEKWNELIEFSFLSEDMKEKYFKLLKERVGRF

Download         Length: 924 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11700.35 Da        Isoelectric Point: 4.3128

>AT274441 WP_289662832.1 NZ_CP119766:c167294-166980 [Flavobacterium sp. CJ75]
MRKAIVYVHGVRAGELLEEGNGSYVFEYDEDYSAEPVSLTMPITHKKYSFLNFPPFFEGLLPEGIMLEGLLKINKIDTKD
YFSQLIATGSDLVGAVTVKEVDYE

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References