Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 4436410..4437093 Replicon chromosome
Accession NZ_CP119754
Organism Superficieibacter sp. HKU1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag P0H77_RS21150 Protein ID WP_276159131.1
Coordinates 4436776..4437093 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag P0H77_RS21145 Protein ID WP_276159130.1
Coordinates 4436410..4436706 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0H77_RS21125 (P0H77_21130) 4432268..4433674 - 1407 WP_176920893.1 replicative DNA helicase -
P0H77_RS21130 (P0H77_21135) 4433738..4434721 + 984 WP_276159127.1 quinone oxidoreductase -
P0H77_RS21135 (P0H77_21140) 4434886..4435128 - 243 WP_276159128.1 envelope stress response protein PspG -
P0H77_RS21140 (P0H77_21145) 4435264..4436274 - 1011 WP_276159129.1 tRNA dihydrouridine(20/20a) synthase DusA -
P0H77_RS21145 (P0H77_21150) 4436410..4436706 - 297 WP_276159130.1 NadS family protein Antitoxin
P0H77_RS21150 (P0H77_21155) 4436776..4437093 - 318 WP_276159131.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P0H77_RS21155 (P0H77_21160) 4437325..4437837 + 513 WP_276159132.1 zinc uptake transcriptional repressor Zur -
P0H77_RS21160 (P0H77_21165) 4437917..4438126 - 210 WP_176920900.1 CsbD family protein -
P0H77_RS21165 (P0H77_21170) 4438342..4438950 - 609 WP_276159133.1 transcriptional repressor LexA -
P0H77_RS21170 (P0H77_21175) 4439060..4439428 - 369 WP_276159134.1 diacylglycerol kinase -
P0H77_RS21175 (P0H77_21180) 4439558..4441978 + 2421 WP_276159135.1 glycerol-3-phosphate 1-O-acyltransferase PlsB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(35-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(39-86)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 12228.09 Da        Isoelectric Point: 9.8034

>T274436 WP_276159131.1 NZ_CP119754:c4437093-4436776 [Superficieibacter sp. HKU1]
MFTFIELHGFSKRRQAFLPDDEFRVFQELLIEDPETGDVIAGTGGFRKIRWSRPGMGKRGGVRVIYYTVTRKGRIYLALI
YPKNEQDDLSEDQKRALKQLSDMLV

Download         Length: 318 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11079.89 Da        Isoelectric Point: 6.4721

>AT274436 WP_276159130.1 NZ_CP119754:c4436706-4436410 [Superficieibacter sp. HKU1]
MKDELFAELLASAEEMVRIEKGEQTPAPEHVHTFSAIDVKAIREATGLKQQDFAMAVGVSYDLVKSWETKRRQPTGAPRK
LLLLLEMNPFIINQLKTI

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References