Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 2308614..2309344 Replicon chromosome
Accession NZ_CP119754
Organism Superficieibacter sp. HKU1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag P0H77_RS10985 Protein ID WP_276164913.1
Coordinates 2309021..2309344 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag P0H77_RS10980 Protein ID WP_276164912.1
Coordinates 2308614..2309030 (-) Length 139 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0H77_RS10965 (P0H77_10970) 2304002..2307049 + 3048 WP_276164909.1 formate dehydrogenase-N subunit alpha -
P0H77_RS10970 (P0H77_10975) 2307061..2307942 + 882 WP_276164910.1 formate dehydrogenase subunit beta -
P0H77_RS10975 (P0H77_10980) 2307935..2308582 + 648 WP_276164911.1 formate dehydrogenase-N subunit gamma -
P0H77_RS10980 (P0H77_10985) 2308614..2309030 - 417 WP_276164912.1 helix-turn-helix domain-containing protein Antitoxin
P0H77_RS10985 (P0H77_10990) 2309021..2309344 - 324 WP_276164913.1 type II toxin-antitoxin system HigB family toxin Toxin
P0H77_RS10990 (P0H77_10995) 2309642..2309782 - 141 WP_276164914.1 stationary-phase-induced ribosome-associated protein -
P0H77_RS10995 (P0H77_11000) 2310006..2310437 + 432 WP_276164915.1 OsmC family protein -
P0H77_RS11000 (P0H77_11005) 2310471..2311250 - 780 WP_276164916.1 hypothetical protein -
P0H77_RS11005 (P0H77_11010) 2311252..2311446 - 195 WP_276164917.1 hypothetical protein -
P0H77_RS11010 (P0H77_11015) 2311500..2312282 - 783 WP_276164918.1 OBAP family protein -
P0H77_RS11015 (P0H77_11020) 2312461..2313648 + 1188 WP_276164919.1 zinc-dependent alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(21-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(83-136)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12866.23 Da        Isoelectric Point: 10.3308

>T274430 WP_276164913.1 NZ_CP119754:c2309344-2309021 [Superficieibacter sp. HKU1]
MHVISQKKLALAAEKYPQFRDELIAMGKIIAKGYFPGPDSLRQIYPTLDNIKYIDKYYVIDIARNRLRVIAIIFFRTQKF
YVRHVYTHKEYDEFVMKCRTKGKTKWL

Download         Length: 324 bp

Antitoxin


Download         Length: 139 a.a.        Molecular weight: 15085.46 Da        Isoelectric Point: 5.2317

>AT274430 WP_276164912.1 NZ_CP119754:c2309030-2308614 [Superficieibacter sp. HKU1]
MAVEEALKAAEAIKRAIPLLVGSTRCEDYDNALSLVEYWLLHDPENPLLELVAAKIAAYEATLPEVAAFRKASAEAPSAL
ATLRILIDQHNLTLSDFKDEIGSKSMVSRVLNGERQLTLAHIKKLAARFGVSPTLFLD

Download         Length: 417 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References