Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1738783..1738967 Replicon chromosome
Accession NZ_CP119571
Organism Staphylococcus aureus strain N08CSA36

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag PZ486_RS08975 Protein ID WP_000482647.1
Coordinates 1738860..1738967 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1738783..1738843 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PZ486_RS08960 (PZ486_08960) 1734313..1734480 - 168 WP_001790576.1 hypothetical protein -
PZ486_RS08965 (PZ486_08965) 1734711..1736444 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
PZ486_RS08970 (PZ486_08970) 1736469..1738232 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 1738783..1738843 + 61 - - Antitoxin
PZ486_RS08975 (PZ486_08975) 1738860..1738967 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
PZ486_RS08980 (PZ486_08980) 1739101..1739487 - 387 WP_000779360.1 flippase GtxA -
PZ486_RS08985 (PZ486_08985) 1739745..1740887 + 1143 WP_001176863.1 glycerate kinase -
PZ486_RS08990 (PZ486_08990) 1740947..1741606 + 660 WP_000831298.1 membrane protein -
PZ486_RS08995 (PZ486_08995) 1741788..1742999 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
PZ486_RS09000 (PZ486_09000) 1743122..1743595 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T274217 WP_000482647.1 NZ_CP119571:c1738967-1738860 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT274217 NZ_CP119571:1738783-1738843 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References