Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 1455171..1455368 Replicon chromosome
Accession NZ_CP119571
Organism Staphylococcus aureus strain N08CSA36

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag PZ486_RS07485 Protein ID WP_001802298.1
Coordinates 1455264..1455368 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1455171..1455209 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PZ486_RS07460 (PZ486_07460) 1451346..1452011 - 666 WP_001024095.1 SDR family oxidoreductase -
PZ486_RS07465 (PZ486_07465) 1452163..1452483 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
PZ486_RS07470 (PZ486_07470) 1452485..1453465 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
PZ486_RS07475 (PZ486_07475) 1453731..1454822 + 1092 WP_000495681.1 hypothetical protein -
PZ486_RS07480 (PZ486_07480) 1455151..1455225 + 75 Protein_1446 hypothetical protein -
- 1455171..1455209 + 39 - - Antitoxin
PZ486_RS07485 (PZ486_07485) 1455264..1455368 - 105 WP_001802298.1 hypothetical protein Toxin
PZ486_RS07490 (PZ486_07490) 1456048..1456206 + 159 WP_001792784.1 hypothetical protein -
PZ486_RS07495 (PZ486_07495) 1456864..1457721 - 858 WP_000370930.1 HAD family hydrolase -
PZ486_RS07500 (PZ486_07500) 1457789..1458571 - 783 WP_031590911.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T274215 WP_001802298.1 NZ_CP119571:c1455368-1455264 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT274215 NZ_CP119571:1455171-1455209 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References